This selection of articles reflects the growing concern for experimental animals and the continuing moral dilemma surrounding the use of animals in research. The increase in knowledge, improvement of health care and creation of useful products that is derived from experimentation on animals, carries the cost of pain and distress that the animals experience, but if such experimentation was not carried out, the alleviation of suffering in the longterm for both man and animals would not be possible. This book addresses on a technical and scientific level, the obligations that man has to animals and to their welfare. It provides insight and information on the high level of professionalism required in the handling of research animals and discusses whether the use of animals in research could be reduced, replaced or refined so as to limit distress. Experimental scientists will find the articles of interest in their endeavor to minimise distress by improving the scientific quality of experimental work.
This selection of articles reflects the growing concern for experimental animals and the continuing moral dilemma surrounding the use of animals in research. The increase in knowledge, improvement of health care and creation of useful products that is derived from experimentation on animals, carries the cost of pain and distress that the animals experience, but if such experimentation was not carried out, the alleviation of suffering in the longterm for both man and animals would not be possible. This book addresses on a technical and scientific level, the obligations that man has to animals and to their welfare. It provides insight and information on the high level of professionalism required in the handling of research animals and discusses whether the use of animals in research could be reduced, replaced or refined so as to limit distress. Experimental scientists will find the articles of interest in their endeavor to minimise distress by improving the scientific quality of experimental work.
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Technology
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Maße
Gewicht
ISBN-13
978-0-444-81417-3 (9780444814173)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Acknowledgements. Contributors. Addresses of Authors. Preface (Ian F.H. Purhase) 1. Animal Experimentation and the Concept of Alternatives (Coenraad F.M. Hendriksen). 2. Current Guidelines and Regulations in Toxicology Research (Herman B.W.M. Koeter). 3. Long-Term Policy in Toxicology (Marcel Roberfroid). 4. The use of Animals in the Production and Quality Control of Biologicals: Current Practice and Possible Alternatives (Coenraad F.M. Hendriksen). 5. Production of Biological Products and the Use of Laboratory Animals (E. Joost Ruitenberg and Peter C. van Mourik). 6. Basic Research in Physiology and Pharmacology, Some Introductory Remarks (Karl J. Obrink). 7. An Overview of the Role of In Vivo and In Vitro Testing in Physiology and Pharmacology (Carol L. Meschter, Guy Mazue and Gary H. Williams). 8. Neurotransmission: Automated In-Vitro Assays (Cor J. de Vos, Anton M.L. van Delft, Thijs de Boer, Ge S.F. Ruight and Joop S. de Graaf). 9. The Role of Animal Experiments and Alternatives in Industrial Pharmacological Research (Rian de Jonge, Jan H. Reinders and Wim J. Pereboom). 10. Experimental Animal Reduction in Connection with Pharmacopoeial Requirements for Pharmaceuticals (Feddo C. Hillen). 11. Education and Animal Experimentation (Bert F.M. van Zutphen). 12. The use of Animals in Veterinary Training (Andrew N. Rowan). 13. Nutritional Factors in Animal Experimentation (Anton C. Beynen). 14. The Role of Animal Husbandry in Promoting Welfare of Laboratory Animals (Ellen P. Reese). 15. The Reduction of Animal Use Through Genetic Control of Laboratory Animals (Michael F.W. Festing). 16. Prevention and Relief of Pain and Distress (Paul A. Flecknell). 17. Clinical Assessment of Pain, Distress and Discomfort (P.H.M. Griffiths). 18. Discomfort and Distress in Rodents During Chronic Studies (Marga H.M. Kuijpers and H.C. Walvoort). 19. Assessment of Distress Through Pathological Examination (Henk C. Walvoort). 20. The Effect of Alternative Methods on the use of Animals in Biomedical Research (Coenraad F.M. Hendriksen). 21. Perspectives (Herman B.W.M. Koeter and Coenraad F.M. Hendriksen).
