This handbook comprehensively explores various facets of stem cells in regenerative medicine, highlighting the interdisciplinary nature of the research. It covers the biology, characteristics, and applications of mesenchymal and non-mesenchymal stem cells in diverse medical contexts. The potential for treating radiation injuries, spinal cord injuries, diabetes, aging-related diseases, osteoarthritis, Alzheimer's disease, and oral surgery is thoroughly investigated, engaging bench scientists and professionals from various fields worldwide.
Furthermore, it delves into the potential of neuronal stem cells for neural repair, myoblast implants for Duchenne muscular dystrophy, and immunotherapy using nongenetically modified natural killer cells. Handbook of Regenerative Medicine: Stem Cell-Based Approach also uncovers the possibilities of botanical leads combined with stem cell therapy and explores the role of stem cells in promoting healthy aging and cancer. Additionally, the book sheds light on the role of cancer stem cells, their intricate role in cancer development and chemoresistance, particulary in lungs, gliomas, and gynecologic cancers, and their significance as targets in cancer treatment for better prognosis.
The chapters discuss the potential of engineering mesenchymal stem cells for bone regeneration and treating intracerebral hemorrhage. Toward the end, the book elucidates cell-free scaffolding for tissue engineering, adult stem cell disease tropism, and the evolving strategies in regenerative medicine. It is intended for researchers, professionals, and academicians in regenerative medicine, stem cell biology, and medical biotechnology.
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Academic, Postgraduate, and Professional Reference
Produkt-Hinweis
Fadenheftung
Gewebe-Einband
Illustrationen
82 farbige Zeichnungen, 53 s/w Tabellen, 1 s/w Abbildung, 107 farbige Abbildungen, 25 Farbfotos bzw. farbige Rasterbilder, 1 s/w Zeichnung
53 Tables, black and white; 82 Line drawings, color; 1 Line drawings, black and white; 25 Halftones, color; 107 Illustrations, color; 1 Illustrations, black and white
Maße
Höhe: 280 mm
Breite: 210 mm
Gewicht
ISBN-13
978-1-032-73519-1 (9781032735191)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Dr. Khawaja Husnain Haider is a Professor of Cellular and Molecular Pharmacology (Stem Cell and Gene Therapy) and Chairman of the Basic Sciences Department (Medical Program) at Sulaiman AlRajhi University. Before his current assignment, he served in several prestigious institutions in various parts of the world. He has also served as Principal Investigator (PI) and Co-PI on multiple National Institute of Health (NIH) funded stem cell research projects. He has been on the editorial boards and invited reviewer panels for several respected international journals. His research focuses on using, either alone or in combination, DNA, miRNAs, and stem cells as "drugs," a topic that has gained popularity in regenerative medicine. He has extensively published on cellular and sub-cellular preconditioning of stem cells and using their conditioned media for cell-free therapy. He has published nearly 350 book chapters, abstracts, and research papers in various books and leading research journals, including Circulation, Circulation Research, Cardiovascular Research, JCMM, the Journal of Biological Chemistry, Cell Cycle, Basic Research in Cardiology, and Antioxidant Redox Signaling. He has also given numerous presentations and edited ten books covering various facets of stem cells and their applications from drug to drug development.
Chapter 1. Mesenchymal Stromal Cell: Basic characteristics and Interaction with the Immune System. Chapter 2. Significant Progress in Stem Cell Treatment for Alzheimer's Disease: A Critical Review. Chapter 3. Regenerative Medicine in Ophthalmology. Chapter 4. Cell Therapy for Diabetes. Chapter 5. Revisiting Preclinical and Clinical Trials of Mesenchymal Stem Cells in Heart Disease to Define a Dose-Response. Chapter 6. Stemming Pain Sensations with Stem Cells. Chapter 7. Osteoarthritis treatment between bio-stimulation and cell therapy. Chapter 8. Cellular Architects of Healing: Mesenchymal Stem Cell-Based Strategies for Fibrosis. Chapter 9. Stem cells and mineralized plasmatic matrix therapy in oral surgery. Chapter 10. Role of stem cell-based therapy in neurodegenerative, ocular, and cardiovascular disease. Chapter 11. Stem Cells Regenerative Therapy in Cardiac Disease: Lessons from Embryonic Development, Current Evidence for Clinical Application and Potential Future Directions. Chapter 12. Challenges And Opportunities in the Study of Bone Marrow-Derived Mesenchymal Stromal Cells: From Where We Stand to Where We Go. Chapter 13. Mesenchymal stem cell-mediated therapy in regenerative medicine. Chapter 14. Routes of Administration of Mesenchymal Stem Cell Therapy in Cardiac Therapy. Chapter 15. Neuronal Stem Cells and Regenerative Medicine: Harnessing the Potential for Neural Repair. Chapter 16. Biomaterial Nanofiber Scaffolds for Neural Regeneration. Chapter 17. Cell-free and Cell-based Therapy in Treating Spinal Cord Injuries. Chapter 18. 20-Year Life Prolongation Achieved through Muscle Regeneration by Implanting 50-Billion Allogeneic Myoblasts into Duchenne Muscular Dystrophy (DMD) Boys. Chapter 19. Reversing Insulin Resistance by Novel Cell-based and Cell-free Therapy Approaches with Skeletal Myoblasts. Chapter 20. Current progress and challenges of non-genetically modified natural killer (NK) cell-based immunotherapy. Chapter 21. Identification of Potential Botanical Drug Leads for Stem Cell Therapy: Cues from Sri Lankan Traditional Medicine. Chapter 22. Cell-based Therapy for Cancer in Regenerative Medicine. Chapter 23. Lung regeneration against lung diseases: a near future reality? Chapter 24. The pivotal role of glioma stem cells in promoting glioma radio-chemoresistance, progression, and recurrence is a topic of significant interest and potential breakthroughs in neurosurgery, oncology, and molecular biology. Chapter 25. Significance of Targeting Cancer Stem Cells in Gynaecologic Cancer. Chapter 26. Role of Stem Cells in diabetes, liver disease, and cancer treatment. Chapter 27. Pluripotent Stem Cells: A Hope to Move Forward for Cardiovascular Applications.
