There is probably no name more closely linked to metathesis than that of Robert H. Grubbs of the California Institute of Technology. His pioneering work has led to the success of this important and fascinating reaction and in this comprehensive three-volume work he presents all its important aspects.
* The standard work on one of the most fascinating reactions in synthesis
* The team of authors reads like a "Who's who" of metathesis
* Clearly divided into catalyst developments, organic synthesis applications and polymer synthesis
* Presents the commercial applications, too
* More than 40 high-quality contributions
* A must-have for every organic and polymer chemist
Rezensionen / Stimmen
"A comprehensive and authoritative 'Handbook of Metathesis' can be nominated for the 'Best publication of the year'."
E-STREAMS
Auflage
Sprache
Verlagsort
Zielgruppe
Für Beruf und Forschung
Organiker, Katalyse-Chemiker, Metallorganiker, Polymerchemiker, Komplexchemiker
Illustrationen
57
221 s/w Abbildungen, 57 s/w Tabellen
Maße
Höhe: 24 cm
Breite: 17 cm
Dicke: 8 cm
Gewicht
ISBN-13
978-3-527-30616-9 (9783527306169)
Schweitzer Klassifikation
Robert H. Grubbs received his Ph.D. from Columbia University for work with Ron Breslow. After a postdoctoral year with Jim Collman at Stanford University, he joined the faculty at Michigan State University. In 1978, he moved to the California Institute of Technology, where he is now the Victor and Elizabeth Atkins Professor of Chemistry. Among many other awards he received the Nobel Prize in 2005 for his research on the metathesis reaction. His research interests include polymer chemistry, organometallic catalysis, and development of new synthetic organic methodology.
Herausgeber*in
California Institute of Technology, Pasadena, USA
Preface
CATALYST DEVELOPMENTS
Introduction
The Role of the "Tebbe Complex" in Olefin Metathesis
The Discovery and Development of High Oxidation State Mo and W Imido Alkylidene Complexes for Alkene Metathesis
From ill-defined to well-defined W alkylidene complexes
Discovery of Well-defined Ruthenium Olefin Metathesis Catalysts
Synthesis of Ruthenium Carbene Complexes
Synthesis of Rhodium and Ruthenium Carbene Complexes with a 16-Electron Count
Mechanism of Ruthenium-Catalyzed Olefin Metathesis Reactions
Intrinsic Reactivity of Ruthenium Carbenes
The Discovery and Development of High Oxidation State Alkylidyne Complexes for Alkyne Metathesis
Well-defined Metallocarbenes and Metallocarbynes Supported on Oxide Support prepared via Surface Organometallic Chemistry
APPLICATIONS IN ORGANIC SYNTHESIS
Introduction
General Ring-Closing Metathesis
Catalytic Asymmetric Olefin Metathesis
Tandem RCM
Ene-Yne Metathesis
Ring Opening Cross Metathesis
Ring Expansion Metathesis Reactions
Olefin Cross-Metathesis
The Olefin Metathesis Reaction in Complex Molecule Construction
Applications of Ring Closing Metathesis to Alkaloid Synthesis
Radicicol and the Epothilones: Total Synthesis of Novel Anti Cancer Agents Using Ring Closing Metathesis
The Use of Olefin Metathesis in Combinatorial Chemistry: Supported and Chromatography-Free Syntheses
Metal-Catalyzed Olefin Metathesis in Metal Coordination Spheres
Alkyne Metathesis
Metathesis of silicon-containing olefins
Commercial Applications of Ruthenium Metathesis Processes
POLYMER SYNTHESIS
Introduction
Living Ring-Opening Olefin Metathesis Polymerization
Synthesis of Copolymers
Conjugated polymers
Stereochemistry of ROMP
Syntheses and Applications of Bioactive Polymers Generated by the Ring-Opening Metathesis Polymerization (ROMP)
Metathesis Polymerization: A Versatile Tool for the Synthesis of Surface-Functionalized Supports and Monolithic Materials
Telechelic Polymers from Olefin Metathesis Methodologies
ADMET Polymerization
Acyclic Diyne Metathesis Utilizing in Situ Transition Metal Catalysts: An Efficient Access to Alkyne-Bridged Polymers
Polymerization of Substituted Acetylenes
Commercial Applications
