Preface
(C. Romanin, W. F. Graier, K. Groschner).-
SECTION 1: SOCE - Fundamental mechanistic concepts
.-
Introduction (J. W. Putney).-
1.1 The STIM-Orai pathway
.-
Structural insights into Ca2+ sensing by stromal interaction molecules
(P. B. Stathopulos, M. Ikura).-
1.2 The STIM-Orai pathway. Orai, the pore-forming subunit of the CRAC channel
(P. G. Hogan).-
1.3 The STIM-Orai pathway. The interactions between STIM and Orai
(R. Schindl, M. Fahrner, M. Muik, I. Derler, C. Romanin).-
1.4 STIM-TRP pathways. The STIM1/Orai/TRPC channels multiple Ca2+ influx complexes
(J. H. Hong, M. S. Kim, K. P. Lee, J. P. Yuan, S. Muallem).-
1.5 STIM-TRP pathways. Function and regulation of TRPC1: Contribution to Ca2+ entry activated by store depletion
(I. S. Ambudkar, K. T. Cheng, H. L. Ong, X. Liu).-
1.6 Microdomain organization and the role of second messengers. Microdomain organization of SOCE signaling
(C. Moreno, L. Vaca).-
1.7 Microdomain organization and the role of second messengers. Store-operated Ca2+ entry: Endogenous messengers and mediators
(V. M. Bolotina).-
SECTION 2: SOCE - Crosstalk between organelle and cellular compartments
.-
Introduction: Ca2+ signaling and gene regulation: An introduction
(A. B. Parekh).-
2.1 New aspects of the contribut
ion of ER to SOCE regulation.
The role of the ER and ER-plasma membrane junctions in the regulation of SOCE
(H. Dingsdale, L. Haynes, G. Lur, A. Tepikin).-
2.2 New aspects of the contribution of ER to SOCE regulation.
The contribution of SERCA to the regulation of SOCE
(J. García-Sancho, M. T. Alonso)
.-
2.3 New aspects of the contribution of ER to SOCE regulation.
TRPC proteins as a link between plasma membrane ion transport and intracellular Ca2+ stores
(
A. Bavencoffe, M. X. Zhu).-
2.4 The role of mitochondria in the activation/maintenance of SOCE.
Store-operated Ca2+ entry and mitochondria
(
A. Spät, G. Szanda).-
2.5 The role of mitochondria in the activation/maintenance of SOCE. Local regulation of plasma membrane channels by mitochondria
(N. Demaurex, M. Frieden).-
2.6 The role of mitochondria in the activation/maintenance of SOCE. The contribution of distinct mitochondrial Ca2+ uptake mechanisms, mitochondrial motility and location to store-operated Ca2+ entry
(R. Malli, W. F. Graier).-
2.7 Tissue specificity. The role of nanospaces between the organellar membranes in smooth muscle Ca2+ signaling
(N. Fameli, A. M. Evans, C. van Breemen).-
2.8 Tissue specificity.
SOCE - implications for Ca2+ handling in endothelial cells
(L. A. Blatter).-
SECTION 3: SOCE - Molecular and cellular (patho)physiology.-
Introduction (J. A. Rosado).-
3.1 Immune system. SOCE mediated by STIM and Orai genes in immune function and disease (S. Feske).-
3.2: Cardiovascular system. STIM1/Orai1-mediated store-operated Ca2+ entry in cardiovascular disease
(R. K. Motiani, M. Trebak).-
3.3: Cardiovascular system. TRPC/Orai-containing channels, Na+/Ca2+ + exchanger and Ca2+ handling in hypertension
(V. A. Golovina).-
3.4: Cardiovascular system. SOCE and TRPC/STIM/Orai signaling in cardiac myocytes
(H. Watanabe, T. Ohba, H. Ito).-
3.5: Cardiovascular system. SOCE as a determinant of cardiac pacemaker activity (D.G. Allen, Y. K. Ju, J. Liu, M. S. Imtiaz).-
3.6: Cardiovascular system. SOCE and Ca2+ handling in platelet dysfunction (J. J. Lopez, G. M. Salido, J. A. Rosado).-
3.7: Cardiovascular system. Store-operated Ca2+ entry in endothelial pathophysiology (K. Groschner, M. Poteser).-
3.8: Nervous system. Pathophysiological perspective of neuronal store-operated Ca2+ signaling (S. Bollimuntha, B. Pani, B. B. Singh).-
3.9: Skeletal muscle. Store-operated Ca2+ entry and STIM/Orai signaling in skeletal muscle (J. A. Stiber, P. B. Rosenberg).-
3.10: Skeletal muscle. Store-operated channels and Ca2
+ handling in muscular dystrophy
(U. T. Ruegg, G. Shapovalov, K. Jacobson, J. Reutenauer-Patte, H. Ismail, O. M. Dorchies, P. Avdonin).-
3.11: Reproductive system. Store-operated Ca2+ entry in germ cells - role in egg activation (Z. Machaty, C. Wang, K. Lee).