Part 1 Regulation of IGF expression: growth hormone signalling between the receptor and the nucleus, J. Schwartz et al; molecular mechanisms for nutritional regulation of genes for IGF-I, IGF-binding proteins, and other plasma proteins, D.S. Straus et al. Part 2 Structural and functional relationships: molecular interactions of IGF-I and IGF-II with their binding proteins and receptors, G.L. Francis et al; unglycosylated "big" IGF-II in non islet cell tumor hypoglycemia (NICTH) and its serum binding, W.H. Daughaday and B. Trivedi. Part 3 Receptors: transmembrane signalling properties of the insulin and IGF-I tyrosine kinase receptors, J.E. Pessin; signal structures on the mannose 6-phosphate/IGF II receptor, T. Braulke et al. Part 4 Binding proteins: similarities in the regulation of hIGFBP-1 and PEPCK gene expression, D.R. Powell et al; biological effects of IGF-regulated IGFBP in cultured human fibroblasts, C.A. Conover et al; regulation and actions of IGF binding protein (IGFBP)-4 and IGFBP-5 in bone - physiological and clinical implications, S. Mohan et al; vascular endothelium, IGFs and IGF binding proteins, R.S. Bar et al. Part 5 Growth, development and differentiation: expression and function of IGFBPs during rodent development, J. Pintar; the roles of IGF-I, IGF-II and IGFBPs in myogenesis, D.Z. Ewton et al; a role for IGF-I during myeloid cell growth and differentiation, K.W. Kelley and S. Arkins. Part 6 Reproduction: regulation of intrafollicular IGFBPs - possible relevance to ovarian follicular selection, E.Y. Adashi; insulin-like growth factor I and the testis target, P.G. Chatelain et al. Part 7 In vivo actions: immunologic effects of IGF-I, R. Clark and P. Jardieu; insulin-like growth factors and the kidney, A. Flyvbjerg and H. Orskov. Part 8 Clinical studies: in vivo use of recombinant human IGF-I - studies in type 1 diabetes, T.D. Cheetham et al; IGF-I treatment of syndromes of growth hormone insensitivity, R.R. Rosenfeld et al. (Part Contents).
