This volume examines advances in the genetics of hematologic disorders. The papers selected for this work were presented at the 6th International Clinical Genetics Seminar in Corfu, Greece in 1990. They deal with hemoglobinopathies and the thalassemias, the erythrocyte enzymopathies, and the hemophilias and blood malignancies viewed from the genetics standpoint. An invaluable resource, this book provides the opportunity for an in-depth look at genetic disorders.
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Gewicht
ISBN-13
978-1-56032-205-4 (9781560322054)
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Schweitzer Klassifikation
Part 1 Introduction: morbid anatomy of the human genome in relation to hematological disorders - role of gene mapping in hematology. Part 2 Thalassemias: cis- and trans-acting elements that participate in the development of the human B-globin gene locus; hemoglobinopathies and erythrocyte enzymopathies in the populations of the USSR. Part 3 Enzymopathies of the red cell: glucose 6-phosphate dehydrogenase deficiency - an update. Part 4 Hemophilia: carrier detection in hemophilia A. Part 5 Leukemias: balanced familial (2;8) translocation in a young girl with ph-positive chronic myelogenous leukemia; heterochromatin polymorphism in patients with malignant diseases; cytogenetic backup of diagnosing and monitoring leukemia. Part 6 Hematological manifestations: Bloom's syndrome - incidence, age of onset, and types of leukemia in the Bloom's syndrome registry; cytogenetics in the 21st century.
