With the advent of molecular biology, pathologists today face a broad and complex range of activities which demand a high degree of technical competence. This volume offers coverage of the new methodology in respect to paediatric pathology, with special emphasis on DNA cytometry. Invited experts describe in detail the basic principles and techniques underlying molecular biological methods, provide practical recipes for these techniques, and illustrate their clinical application in various infectious, neoplastic and hereditary diseases. Attention is also given to the use of flow and image cytometry to measure cellular DNA content in childhood tumours and to improve the diagnosis of hydatidiform moles. Illustrating the essential role of molecular biology in relating structure, function, pathogenesis and diagnosis, this reference is designed for all those interested in flow cytometry and other recent methodology.
Reihe
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
31 Schaubilder, 16 Tabellen
31 figs., 16 tab.
Maße
Gewicht
ISBN-13
978-3-8055-5377-3 (9783805553773)
Schweitzer Klassifikation
Founders of paediatric pathology, H. Gore and K. Benirschke; paediatric pathology in the time of AIDS, H.S. Rosenberg; paediatric molecular pathology, T. O'Leary and C.F. Wright; applications of DNA cytometry in paediatric pathology, T. Gansler; insulin-like growth factor production by childhood solid tumours, A.J. Garvin et al; hydatidiform moles and the use of flow cytometry in their diagnosis, C.L. Hitchcock et al.