Abbreviations; An introduction to modern methods of DNA synthesis; Preparation of protected deoxyribonucleosides; Solid phase synthesis of oligodeoxyribonucleotides by the phosphite-triester method; Solid-phase synthesis of oligodeoxyribonucleotides by the phosphotriester method; Chromotographic purification of synthetic oligonucleotides; Purification and sequence analysis of synthetic oligodeoxynucleotides; Chemical synthesis of small oligoribonucleotides in solution; Enzymatic synthesis of oligoribonucleotides; Appendices; Index