Dedication Acknowledgements Series Editor's Note: Lunsford, L.D. Foreword: Anderson, W.F. Introduction: Freese, A.; Janson, C.; Leone, P.; Simeone, F.A. The Spine and Spinal Cord The Molecular Basis of Intervertebral Disc Degeneration: Leo, B.M.; Walker, M.H.; Anderson, D.G. Genetics of Degenerative Disc Disease: Kurpad, S.N.; Lifshutz, J. Gene Therapy for Degenerative Disc Disease: Kim, J.; Gilbertson, L.G.; Kang, J.D. Bone Morphogenetic Proteins. Spinal Fusion Applications: Bomback, D.A.; Grauer, J.N. Cellular and Gene Therapy Approaches to Spinal Cord Injury: Steinmetz, M.P.; Liu, J.K.; Boulls, N.M. Neural Stem Cell Transplantation for Spinal Cord Repair: Iwanami, A.; Ogawa, Y.; Nakamura, M.; Kaneko, S.; Sawamoto, K.; Okano, H.J.; Toyama, Y.; Okano, H. Functional and Restorative Molecular Neurosurgery Contemporary Applications of Functional and Stereotactic Techniques for Molecular Neurosurgery: House, P.A.; Rao, G.; Couldwell, W. Xeno-Neurotransplantation: Schumacher, J.M. Adeno-Associated Viral Vectors for Clinical Gene Therapy in the Brain: Samulski, R.J.; Giles, J. Molecular Mechanisms of Epilepsy and Gene Therapy: Telfeian, A.; Celix, J.; Dichter, M. Emerging Treatment of Neurometabolic Disorders: Brady, R.O.; Brady, R.O., Jr. Gene Therapy for Parkinson's Disease: Hadaczek, P.; Daadi, M.; Banklewicz, K. Simplifying Complex Neurodegenerative Diseases by Gene Chip Analysis: Scherzer, C.R.; Gullans, S.R.; Jensen, R.V. Molecular Pathology of Dementia. Emerging Treatment Strategies: Gouras, G.K. Expanding the Role of Deep Brain Stimulation from Movement Disorders to Other Neurological Diseases: Leone, M.; Franzini, A.; Broggi, G.; Bussone, G. Molecular Mediators of Pain: Chaudhary, P.; Burchiel, K. Gene Transfer in the Treatment of Pain: Fink, D.; Mata, M.; Glorioso, J.C. Neurovascular Disorders Gene Discovery Underlying Stroke: Barone, F.C.; Read, S.J. Molecular Mediators of Hemorrhagic Stroke: Macdonald, R.L. Advances towards Cerebrovascular Gene Therapy: Watanabe, Y.; Heistad, D.D. Ex vivo Gene Therapy and Cell Therapy for Stroke: Kondziolka, D.; Sheehan, J.; Niranjan, A. Neuro-Oncology Neurosurgical Applications for Polymeric Drug Delivery Systems: Wang, P.P.; Brem, H. Immunotherapy Strategies for Treatment of Malignant Gliomas: Harshyne, L.; Flomenberg, P.; Andrews, D.W. Glioma-Genesis. Signaling Pathways for the Development of Molecular Oncotherapy: Kapoor, G.S.; O'Rourke, D.M. Oncolytic Viral Therapy for Glioma: Lamfers, M.L.M.; Visted, T.; Chiocca, E.A. Molecular Neurosurgery in the Pituitary Gland. Gene Transfer as an Adjunctive Treatment Strategy: Castro, M.G.; Jovel, N.; Goverdhana, S.; Hu, J.; Yu, J.; Ehtesham, M.; Yuan, X.; Greengold, D.; Xiong, W.; Lowenstein, P.R. Stem Cells for Targeting CNS Malignancy: Yip, S.; Sidman, R.L.; Snyder, E.Y. Autor Index Subject Index