Renowned authors from 14 countries have contributed to this book. It consists of 24 chapters on the state-of-the-art of the synthesis of nonaromatic nitrogen heterocycles, including recent developments in the most widely used reactions and also in new ones. Enantioselective synthesis and catalysis, and topics such as photocatalysis, microwave-assisted synthesis, ionic liquids and others, are also covered. The first 14 chapters after the introduction are dedicated to the synthesis of rings having one specific size,
namely three-, four-, five-, six- and seven-membered rings, single or fused to other rings, in order of increasing ring
size. Some concentrate on specific reactions such as cycloaddition reactions, hydroamination and dearomatization reactions, others inspect the many ways possible to obtain a specific ring. Later chapters cover topics such as the reactions of oximes and the reactions of nitrones, enantioselective radical reactions, the utilization of microwaves in synthesis, biocatalysis and photocatalysis. Sustainable procedures for obtaining nitrogen-containing heterocyclic salts are discussed, and the final chapter considers non-covalent interactions and how they can influence the synthesis of N-containing heterocycles, as well as catalysis and materials design.
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Maße
Höhe: 297 mm
Breite: 137 mm
Dicke: 56 mm
Gewicht
ISBN-13
978-1-119-70870-4 (9781119708704)
Schweitzer Klassifikation
Herausgeber*in
Universidade de Lisboa, Lisbon, Portugal
List of Contributors
Preface
List of Common Abbreviations
Chapter 1. Introduction
Chapter 2. Recent Advances in the Synthesis of Aziridines
Chapter 3. Synthesis of Four-Membered Aza-Heterocycles Through Catalytic [2+2] Cycloaddition Reactions Assisted by Metal Complexes
Chapter 4. Therapeutic Potentials of ß-Lactam: A Scaffold for New Drug Development
Chapter 5. Progress in the Synthesis Of Chiral Nitrogen Heterocycles Mainly by Asymmetric [3+2] Cycloadditions
Chapter 6. Synthesis of Five-Membered N-Heterocycles by Enantioselective, Metal-Catalyzed, Intramolecular, Hydroamination of Alkenes
Chapter 7. Recent Advances in the Synthesis of Isoxazolidines
Chapter 8. Recent Advances in the Stereoselective Synthesis of Pyrrolizidin-3-ones
Chapter 9. Synthesis of Spirooxindoles by Multicomponent Reactions
Chapter 10. Modern Catalytic, Enantioselective Approaches to Piperidines
Chapter 11. Organocatalytic Enantioselective Dearomatization Reactions for the Synthesis of Nitrogen Heterocycles
Chapter 12. Synthesis of Dihydroquinolines in the XXI Century
Chapter 13. Asymmetric Aza-Diels-Alder Reaction-Application in the Synthesis of Natural Products
Chapter 14. Synthesis of Saturated Nitrogen-Containing Heterocycles Through [5+2] Cycloadditions
Chapter 15. Modern Methods for the Synthesis of 1,4-Oxazepanes and Their Oxo-Derivatives
Chapter 16. Non-Aromatic Nitrogen Heterocycles Derived from Metal-Involving Reactions of Oximes
Chapter 17. Metal-Catalyzed and Metal-Mediated Reactions of Nitrones Leading to Non-Aromatic Nitrogen Heterocyclic Systems
Chapter 18. Recent Developments in the Chemical Synthesis of Amaryllidaceae Alkaloids
Chapter 19. Enantioselective Synthesis of Nitrogen Heterocycles by Radical Reactions
Chapter 20. Recent Applications of Microwave-assisted Cyclizations Promoted by Polyphosphoric Acid Esters to the Synthesis of Nitrogen Heterocycles
Chapter 21. Biocatalysis Towards the Synthesis of Chiral Amines
Chapter 22. Photocatalytic Synthesis of Nitrogen-Containing Heterocycles
Chapter 23. Sustainable Synthetic Approaches for Nitrogen-Containing Heterocyclic Salts
Chapter 24. Noncovalent Interactions in N-Heterocyclic Chemistry: Synthesis, Catalysis and Design of Materials
