Based on the author's extensive experience at the Memorial Sloan-Kettering Cancer Center in New York, this volume is a definitive reference on diagnostic transmission electron microscopy of tumors. It is really two essential books in one-- a comprehensive guide to current ancillary procedures for evaluating human tumors; and an encyclopedic reference on the diagnostically significant ultrastructural and immunophenotypic features of virtually every human tumor. Nearly 1,000 electron micrographs and 37 easy-to-use tables complement the text. The opening chapters describe ancillary procedures for evaluating tumors, including tissue preparation methods, and examine the nuclear, cytoplasmic, cell surface, and extracellular constituents seen in human neoplasms. The book then covers-- in 103 sections-- the ultrastructural features of most human neoplasms, correlated with clinicopathological, immunohistochemical, and, where applicable, cytogenetic data. Most sections include a brief discussion of the differential diagnosis.
Cross-references enable the reader to look up either a structure--to locate in which tumors it is found--or the diagnostic ultrastructural features of a specific tumor type
Based on the author's extensive experience at the Memorial Sloan-Kettering Cancer Center in New York, this volume is a definitive reference on diagnostic transmission electron microscopy of tumors. It is really two essential books in one-- a comprehensive guide to current ancillary procedures for evaluating human tumors; and an encyclopedic reference on the diagnostically significant ultrastructural and immunophenotypic features of virtually every human tumor. Nearly 1,000 electron micrographs and 37 easy-to-use tables complement the text. The opening chapters describe ancillary procedures for evaluating tumors, including tissue preparation methods, and examine the nuclear, cytoplasmic, cell surface, and extracellular constituents seen in human neoplasms. The book then covers-- in 103 sections-- the ultrastructural features of most human neoplasms, correlated with clinicopathological, immunohistochemical, and, where applicable, cytogenetic data. Most sections include a brief discussion of the differential diagnosis.
Cross-references enable the reader to look up either a structure--to locate in which tumors it is found--or the diagnostic ultrastructural features of a specific tumor type
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
37 tables, 957 half-tones, 1 line drawing, 12 colour illustrations
Maße
Höhe: 279 mm
Breite: 216 mm
Gewicht
ISBN-13
978-0-7817-0042-9 (9780781700429)
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Schweitzer Klassifikation
Part 1 Ancillary procedures for evaluating human tumours: transmission electron microscopy; other types of electron microscopy; immunohistochemistry and immunoelectron microscopy; tumour cytogenetics; molecular pathology. Part 2 The nucleus: chromosomes and chromatin; nuclear envelope - fibrous lamina; nucleolus; nuclear configurations; nuclear inclusions. Part 3 The cytoplasm: organelles; inclusions; intracytoplasmic fibrils - cytoskeleton. Part 4 The cell surface: cell membrane specializations; cell junctions. Part 5 Extracellular constituents: collagen; elastic fibers; amyloid - amyloidoma; psamomma bodies; basement membrane. Part 6 Ultrastructural features of specific human neoplasms: with clinicopathologic, immunohistochemical, and cytogenetic correlations (103 sections).