Introduction. 1: Primer immunology/autoimmunity. 2: The target organ: Embryology, biochemistry and physiology. 3: NOD Mouse and BB Rat: Genetic and immunologic function. 4: The role of T cells in beta cell damage in NOD mice and humans. 5: Inflammatory mediators and development of autoimmune diabetes. 6: The immunobiology of pancreatic islet transplantation. 7: Type I diabetes mellitus of man: Genetic susceptibility and resistance. 8: Autoimmune polyendocrine syndromes. 9: Epidemiology of Type I diabetes. 10: Humoral autoimmunity. 11: Natural history of pre-diabetes. 12: Clinical trials for the prevention of Type I diabetes. 13: Selected Type I diabetes research resources. 14: Essays on disease pathogenesis
