Co-authored by three of the world's foremost authorities - all directors of the International Cerebral Blood Flow and Metabolism Society - this work is a text and reference on cerebral blood flow and metabolism. Unlike other books, which focus on a single aspect of cell metabolism or the cerebral circulation, this volume covers the entire field in a systematic and coherent way and synthesizes the diverse body of basic science and clinical literaturue. The reader should gain a complete understanding of the anatomical, physiological, and pharmacological bases of a cerebral circulation, its regulation in health and disease, and the pathophysiological disturbances occurring in cerebrovascular disorders. The value of the book is further enhanced by the authors' discussions of future directions for research and therapeutic intervention.
Co-authored by three of the world's foremost authorities - all directors of the International Cerebral Blood Flow and Metabolism Society - this work is a text and reference on cerebral blood flow and metabolism. Unlike other books, which focus on a single aspect of cell metabolism or the cerebral circulation, this volume covers the entire field in a systematic and coherent way and synthesizes the diverse body of basic science and clinical literaturue. The reader should gain a complete understanding of the anatomical, physiological, and pharmacological bases of a cerebral circulation, its regulation in health and disease, and the pathophysiological disturbances occurring in cerebrovascular disorders. The value of the book is further enhanced by the authors' discussions of future directions for research and therapeutic intervention.
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
29 tables, 261 line drawings, 33 half-tones, 11 colour illustrations
Maße
Höhe: 254 mm
Breite: 178 mm
Gewicht
ISBN-13
978-0-88167-918-2 (9780881679182)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Autor*in
Director, Centre Cyceron, University of Caen, Caen, France
Professor of Neuroscience, Wellcome Neuroscience Group, University of Glasgow, Scotland
Part 1 The anatomic bases: general and comparative anatomy of the cerebral circulation; the blood vessel wall - endothelial and smooth muscle cells; perivascular nerve fibres in brain vessels; functional circuitry. Part 2 The physiological bases: vascular smooth muscle reactivity in vitro and in situ; the blood-brain barrier - permeability and substrate transport; energy generation in the central nervous system; neurotransmitters - metabolic and vascular effects in vivo. Part 3 The pharmacological bases: adrenergic mechanisms; dopamine; 5-hydroxytryptamine; acetylcholine; histamine; adenosine; prostaglandins and other elcosanoids; calcium antagonists; anaesthetic agents; neuropeptides; aminobutyric acid (GABA); glutamic acid. Part 4 Fundamental responses of the cerebral circulation: aspects on methods used in vivo; changes in arterial gas tensions; autoregulation - arterial and intracranial pressure; functional depression and stimulation. Part 5 Disordered control - pathophysiological aspects: disturbed cerebral autoregulation; disordered substrate supply; cerebral ischemia; migraine and cluster headache; subarachnoid haemorrhage; the aged brain.
