The first volume in a three-part series, "Insulin Secretion" covers recent findings on the physiology and biochemistry of insulin release in both normal and diabetic states, highlighting the signal transduction system. This complex system includes traditional elements, such as hormone receptors, along with newly described components, such as G-proteins, intracellular kinases, and derivatives of the plasma membrane phospholipids. It reflects the various mechanisms by which hormones and nutrients interacting with B-cells influence the synthesis of insulin and islet cell secretory processes.
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ISBN-13
978-0-471-50393-4 (9780471503934)
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Schweitzer Klassifikation
Pancreatic Islets: Morphology, Organization, and Physiological Implications (S. Bonner-Weir); The Insulin Gene and Its Regulation (M. Permutt); Insulin Structure and Biosynthesis (G. Gold); Cell Biology of Insulin Secretion (B. Dranzin & R. Dahl); Electrophysiology of the Pancreatic B-Cell (I. Atwater, et al.); Phosphoinositide Turnover in the Stimulus-Response Coupling of Pancreatic Beta Cells (W. Zawalich); Role of Phospholipase Activation in Signal Transduction in the Pancreatic Beta Cell (S. Metz); Regulation of Insulin Release by Calcium (R. Boyd III, et al.); Intracellular Signals and Protein Phosphorylation: Regulatory Mechanisms in the Control of Insulin Secretion From the Pancreatic Beta Cell (N. Fleischer & J. Erlichman); Intraislet Hormone Regulation (K. Sussman); Molecular BIology and Autoimmunity of Type I Diabetes Mellitus (P. Coleman, et al.).Genetics of Diabetes Mellitus (C. Vadheim, et al.); Noninsulin-Dependent Diabetes Mellitus: Current Concepts of Pathogenesis (J. Leahy & G. Weir); Index; Contents of Volume II: Insulin Action; Contents of Volume III: Complications of Diabetes Mellitus.
