The understanding of (patho)physiological processes - the biosynthesis of biomolecules such as enzymes, nucleic acids, and secondary metabolites; the pathways of signaltransduction; or the function of pharmaceutical agents - is of increasing importance not only for drug research but also for the development of new synthetic methods in organic chemistry and biochemistry. In a truly interdisciplinary way bioorganic chemistry unites the central questions of biochemistry, medicinal chemistry, organic chemistry, and spectroscopy.
This book fills a void in this rapidly growing field of chemistry and gives a thorough yet understandable introduction for advanced students and researchers alike. Contributions of more than sixty scientists provide a topical overview of recent advances in: drug development based on natural products; the biosynthesis, activity, and application of enzymes; carbohydrates; peptides; nucleic acids; analytical methods in bioorganic chemistry.
This book will be an appetizer for all - students and researchers alike - seeking orientation in this fascinating field of chemistry.
Rezensionen / Stimmen
Rezensionen:
"...bietet dieses Buch einen guten Überblick und Einstieg sowohl von chemischer als auch von biologischer Seite...Für alle, die Interesse an spannenden neuen Themen wie enzymatische Diels-Alder Reaktionen oder die Synthese von Oligonucleotiden mit Polypeptid Rückgrat anstatt des Zucker/Phosphat Rückgrats werden an diesem Buch ihre Freude haben." KVV d. Fachschaft Biologie-und Chemiewissenschaften Potsdam
Auflage
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Organiker, Biochemiker, Studenten höherer Semester, Dozenten, Bibliotheken
Illustrationen
28
155 s/w Abbildungen, 28 s/w Tabellen
Maße
Höhe: 24 cm
Breite: 17 cm
Dicke: 2.5 cm
Gewicht
ISBN-13
978-3-527-29665-1 (9783527296651)
Schweitzer Klassifikation
>Ulf Diederichsen studied Chemistry in Freiburg, Germany, with a diploma work in organic synthesis and completed his Ph.D. in 1993 under the supervision of Albert Eschenmoser at the ETH Zuerich working on homo- and glucose-DNA. Following postdoctoral work on radical chemistry at the University of Pittsburgh, USA, in the group of Dennis Curran, he gained his habilitation at the Technical University Munich, Germany, with Horst Kessler as mentor. In 1999, he was appointed professor of Organic Chemistry at the University Wuerzburg, Germany, until joining the Georg-August-University in Goettingen, Germany, in 2001 as full professor of Organic Chemistry. He was visiting professor at the LMU Munich and Goering Visiting Professor at the University of Wisconsin, USA. In 1999 he got the Karl Winnacker stipend and Hellmut-Bredereck award and is an ordinary member of Goettingen Academy of Sciences and Humanities since 2012
Herausgeber*in
Technical University Munich, Garching, Germany
University of Hamburg, Germany
University of Paderborn, Germany
Vrije Universiteit Amsterdam, The Netherlands
DRUGS AND SEARCH FOR LEAD STRUCTURES
Marine Alkaloids
Leukotriene Derivates
Diazoketones for the Synthesis of Beta-Lactams
Selenium Compounds in Biochemical Oxidations
Galaktophingolipid, etc
ENZYMOLOGY
Enzyme Catalyzed Diels-Alder Reactions
Enzymatic Halogenation in Bacteria
Biotransformations in the Stereoselective Synthesis of Cyclophanes, etc
CARBOHYDRATES
Mannosid Clusters
Glycoconjugates in Cancer Therapy, etc
PEPTIDES
Cyclodepsipeptides
Synthetic Adrenaline and Peptide Receptors
Substituted and Beta-Amino Acids as Building Blocks for Peptide Mimetics
Carbohydrate-Protein Interactions, etc.
NUCLEIC ACIDS
Reparing Dna
In Vitro Selection
Studies on Hairpin Ribozymes
New Pna Buiding Block for Antisense Research, etc.
BIOCHEMISTRY
Activity of Neuropeptide Y
Oligosaccharide Antibiotics
Biosynthesis of Plant Xanthones
Manipulating Intracellular Signal Transductions
Methyl-Transfer Reactions, etc.
SYNTHETIC AND ANALYTICAL METHODS
Constitutional Assignment of Marine Natural Products
Radical Induced Reactions in Biological Systems
Multivariate Analysis of Biotransformations, etc.