Part 1 Experimental pathophysiology: oxidative damage in the pathogenesis of liver cirrhosis, M. Parola et al; from ischemic injury to post-ischemic response - events in the parenchymal liver cells, A. Bernelli-Zazzera; the anoxic injury in hepatocytes, A. Gasbarrini et al; cell death and regeneration in liver tissue, R. Mancini et al; membrane fluidity and liver pathophysiology, D. Alvaro et al; hepatic uptake of organic anions - different mechanisms and putative membrane carrier proteins, A.M. Torres and C. Tiribelli; regulation of bile acid synthesis in humans, M. Bertolotti et al; role of the T cell response to hepatitis B virus (HBV) nucleocapsid antigen in the pathogenesis of HBV infection, F. Fiaccadori et al. Part 2 Epidemiology and clinical pathophysiology: natural history of chronic HCV infection, G. Giusti et al; epidemiological aspects of hepatitis C virus infection in southern Italy, O. Schiraldi; hepatitis C virus and autoimmune chronic hepatitis, S. Magrin et al; immunodetection of hepatitis C virus (HCV)-related antigens in tissues - problems and perspectives, D. Sansonno et al; hormonal regulation of hepatic amino acid conversion into urea, G. Marchesini et al; extracellular matrix structure and regulation in normal and fibrotic liver, S. Milani et al. Part 3 Clinical aspects: prognostic and therapeutic implications of splanchnic hemodynamic evaluation in cirrhosis, A. Gatta et al; blood pressure and heart rate during liver cirrhosis, F. Veglio et al; hormone metabolism and liver disease - implications in adrenal, bone and gonadal pathophysiology, R. Naccarato et al. Part 4 Complications and therapy in liver diseases: pathogenesis and diagnosis of hepatorenal syndrome, P. Gentilini et al; effect of interferon alone or after prednisone withdrawal in children with chronic hepatitis B, R. Utili et al; clinical management of primary biliary cirrhosis, M. Podda et al; efficacy of surveillance programs of cirrhotic patients in the early diagnosis and treatment of HCC, L. Bolondi et al; the natural history of hepatocellular carcinoma, G. Covini et al; surgical approach to portal hypertension, G.P. Spina et al; orthotopic liver transplantation for chronic viral hepatitis - the Turin experience, M. Badini et al; the role of endotoxin in liver disease, D. Scevola et al.