This highly interdisciplinary book may serve as an introduction for
biologists, mathematicians and physicists to key questins in cellular
systems which can be studied with mathematical models. Recent model
approaches are presented with applications in cellular metabolism,
intra- and intercellular signaling, cellular mechanics, network dynamics
and pattern formation. In addition, applied issues such as tumor cell
grow
Reihe
Auflage
Softcover reprint of the original 1st ed. 2004
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für Beruf und Forschung
Research
Illustrationen
23
102 s/w Abbildungen, 23 farbige Abbildungen
X, 451 p. 125 illus., 23 illus. in color.
Maße
Höhe: 235 mm
Breite: 155 mm
Dicke: 26 mm
Gewicht
ISBN-13
978-3-0348-9614-6 (9783034896146)
DOI
10.1007/978-3-0348-7895-1
Schweitzer Klassifikation
to Part I.- A Functional Dynamics Approach to Modelling of Glycolysis.- Temperature-Compensation in Biological Clocks:Models and Experiments.- Metabolic Control Analysis of the ATPase Network in Contracting Muscle:Regulation of Contractile Function and ATP Free Energy Potential.- En Route for Systems Biology: In Silico Pathway Analysis and Metabolite Profiling.- to Part II.- Presynaptic Calcium Dynamics of Neurons in Answer to VariousStimulation Protocols.- Mathematical Modeling of Signaling Cascades: Principles and Future Prospects.- Collective Behavior of Membrane Channels: Electro-physiological Studies on Gap Junctions.- Modelling of Periodic Intercellular Ca2+ Waves.- Travelling Waves as a Mechanism of Pattern Generation in Discrete Cell Lattices.- Design and Operation: Keys to Understanding Biological Systems.- to Part III.- Biopolymer Dynamics.- Micromechanics of Molecular Motors: Experiments and Theory.- The Role of Osteocalcin in the Remodeling of Biomimetic Hydroxyapatite-Collagen Materials for Bone Replacement.- Cell Shape Normalization of Normal and Haploinsufficient NF1-Melanocytes by Micro-Structured Substrate Interaction.- Quantification of Shear Stress-Induced Cell Migration in Endothelial Cultures.- to Part IV.- Constructive and Dynamical Systems Approach to Life.- Coherent Dynamics in Networks of Single Protein Molecules.- Gene Regulatory Networks: A Discrete Model of Dynamics and Topological Evolution.- Evolutionary Reconstruction of Networks.- Modelling Simple Biochemical Networks.- On the Evolution of Information in the Constituents of Regulatory Gene Networks.- to Part V.- Biological Relevance of Tissue Liquidity and Viscoelasticity.- Reinforcement of Cytoskeleton-Matrix Bonds and Tensiotaxis: A Cell-Based Model.- Simulation of Haematopoietic Stem Cell Organisation Using a Single Cell Based Model Approach.- Pattern Formation in an Interacting Cell System: Rippling in Myxobacterial Aggregates.- to Part VI.- Molecular and Cellular Analysis of De Novo Pattern Formation in Hydra.- The Small Freshwater Polyp Hydra as a Model for Axis Formationin Higher Organisms.- Cell Migration, Cell Fate and Pattern Formation During Head Development in Lungfishes and Amphibians.- Cell-Based Modelling of Tissues.- to Part VII.- Cell-Based Models of Avascular Tumor Growth.- Solid Tumor Invasion: The Importance of Cell Adhesion.- Interrelationship of Tumor and Immune System.- Nonlinear Dynamics and Statistical Physics of Models for the Immune System.- Stochastic Model of Influenza Virus Fusion.- Spatio-Temporal Aspects of a Dynamical Disease: Waves of Spreading Depression.- List of contributors.- Color Plates.