Genome analysis has undergone a period of explosive growth in recent years. This book describes up-to-date methods for genome mapping, arranged in order of increasing resolution, from linkage analysis to restriction mapping. Topics covered include linkage mapping of human, animal, and plant genomes; mapping of quantitative trait loci; radiation hybrid mapping; HAPPY mapping; somatic cell hybrids; flow-sorted and microdissected chromosomes; fluorescence in situ hybridization; contig assembly; chromosome walking; and long-range restriction mapping. Two appendices describe sources of freely available biological and computational resources relevant to genome analysis.
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
3 colour plates, 21 halftones, 28 line figures, bibliography
ISBN-13
978-0-19-963631-0 (9780199636310)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
1: Human linkage mapping. 2: Linkage mapping of plant and animal genomes. 3: Linkage mapping of quantitative trait loci in plants and animals. 4: Radiation hybrid mapping. 5: HAPPY mapping. 6: Construction and use of somatic cell hybrids. 7: The use of flow-sorted chromosomes in genome mapping. 8: The use of microdissected chromosomes in genome mapping. 9: Fluorescence in situ hybridization. 10: Contig assembly by fingerprinting. 11: Chromosome wallking. 12: Long-range restriction mapping of genomic DNA. Appendix 1 Core list of suppliers. Appendix 2 Non-commercial source for genome mapping. Appendix 3 Bioinformatics for genome mapping
