This volume contains papers presented at the Ninth International Conference on Second Messengers and Phosphoproteins. The papers highlight advances in the rapidly-evolving field of signal transduction. The findings presented should be significant to researchers in all biomedical fields, including pharmacology, molecular biology, the neurosciences and physiology. The contributors offer insights into fundamental cell signalling mechanisms and explore the role of these mechanisms in physiological and pathophysiological responses in a variety of systems. Coverage includes topics such as growth factors and tyrosine protein kinases; MAP kinases; Fos-Jun and gene regulation; special signalling systems; protein phosphatases and metabolic pathways; calcium and ion channels; cyclic GMP and cyclic AMP; and receptors and G proteins. The findings presented should be significant to researchers in all biomedical fields, including pharmacology, molecular biology, the neurosciences and physiology.
Reihe
Auflage
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
72 line illustrations, 10 halftones, 16 tables
Maße
Höhe: 235 mm
Breite: 155 mm
Dicke: 19 mm
Gewicht
ISBN-13
978-0-397-51685-8 (9780397516858)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Role of phosphatidylinositol 3-OH kinase in Ras signalling; from phosphorylase to phosphorylase kinase; intrasteric regulation of protein kinases; specificity in protein-tyrosine kinase signalling; signalling through protein kinase cascades with reference to the MAPK pathway; coupling transcription to signalling pathways - cAMP and nucleus fractor CREM; cyclic nucleotide-gated channels and calcium - an intimate relation; chemoattractant receptor signalling - G protein-dependent and -independent pathways; mitochondrial a-Keto acid dehydrogenase kinases - a new family of protein kinases; phosphatases as partners in signalling networks; the cAMP pathway in thyroid - from the TSH receptor to mitogenesis and tumorigenesis; CA2+/calmodulin-dependent myosin light chain kinases; cascade activition of the calmodulin kinase family; modulation of sodium and calcium channels by protein phosphorylation and G proteins; interruption of specific guanylyl cyclase signalling pathways; structure, function, and regulation of human cAMP-dependent protein kinases; structural order of the slow and fast intrasubunit cGMR binding sites of type 1x cGMP-dependent protein kinase; the pseudosubstrate sequences alone are not sufficient for potent autoinhibition of cAMP-dependent protein kinases as determined by synthetic peptide analysis; recent advances in the study of CA2+/CaM activated phosphodiesterases - expression and physiological functions; specificity and complexity of receptor-G protein interaction; G-protein-coupled receptors and their regulation; Rab3A-rabphilin-3A system in neurotransmitter release.
