Taking a convenient benchtop format, this book presents methods for easy adaptation to new systems. It includes comprehensive protocols for "model" receptor techniques (radioligand binding, solubilization and purification). The book describes the methodology for the following receptors: bombsin/GRP, cholecystokinin, endothelin, fast nerve growth factor, gastrin-releasing peptide, insulin, insulin-like growth factors, interleukin 1, melanotropin, melatonin, natriuretic hormone, neurokinin, neurotensin, PACAP, pancreatic polypeptide, serotonin, steroids, transferrin, and vasoactive peptides.
Taking a convenient benchtop format, this book presents methods for easy adaptation to new systems. It includes comprehensive protocols for "model" receptor techniques (radioligand binding, solubilization and purification). The book describes the methodology for the following receptors: bombsin/GRP, cholecystokinin, endothelin, fast nerve growth factor, gastrin-releasing peptide, insulin, insulin-like growth factors, interleukin 1, melanotropin, melatonin, natriuretic hormone, neurokinin, neurotensin, PACAP, pancreatic polypeptide, serotonin, steroids, transferrin, and vasoactive peptides.
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Elsevier Science Publishing Co Inc
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Für höhere Schule und Studium
Für Beruf und Forschung
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ISBN-13
978-0-12-185272-6 (9780121852726)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Steroid receptors in the central nervous system, L.M. Freeman and S.M. Breedlove; membrane receptor for glucocorticoids in mammalian neurons, Y. Cehn, et al; interleukin-1 receptors in the brain-endocrine-immune axis, T. Takao and E.B. De Souza; vasoactive peptides and their receptors, D. Regoli, et al; melanotropin receptors of the brain, J.B. Tatro; melatonin binding sites, E.L. Bittman; transferrin receptors in the central nervous system, B. Giometto, et al; binding sites of pituitary adenylate cyclase activating polypeptide (PACAP) in human brain, D.M. Smith and S.R. Bloom; role of cholecystokinin type B receptor in nociception studied with peptide agonists and antagonists, Z. Wiesenfeld Hallin and X.-J. Xu; cholecystokinin receptors - radioligand binding and affinity labeling, M.P. Lutz and L.J. Miller; endothelin receptors in neural systems, P.G. Lysko and P. Nambi; natriuretic peptide receptors, V.T.F. Yeung, et al; structural and functional identification of insulinlike growth factor receptors, S. Gammeltoft; methods for studying central serotonergic receptors, P.M. Whitaker-Azmitia; analysis of serotonin 5-HT1A receptors in primary neuronal culture, B.C. Swarzenski, et al; characterization of the bombesin/GRP receptor in Swiss 3T3 fibroblasts, I. Zachary, et al; receptors for bombesin-like peptides in the rat central nervous system, E.E. Ladenheim, et al; retinal insulin receptors, S.A. Rosenzweig; pancreatic polypeptide receptors in rat brain, D.C. Whitcomb; neurotensin receptors in primary culture of neurons, J. Mazella, et al; analysis of the structure and function of the fast nerve growth factor receptor, A.A. Welcher; solubilization and physicochemical characterization of 5-HT3 receptor binding sites, M.C. Miquel, et al; solubilization and characterization of the receptor for gastrin-releasing peptide, R. Kris, et al; assays for pituitary adenylate cyclase activatin peptide (PACAP) receptors coupled to adenylate cyclase - comparison between rat brain and human neuroblastoma cells, J. Christophe, et al.
