Comprehensive Chirality, Second Edition is the definitive ten-volume reference, offering a thorough exploration of chiral research and application. This extensively updated edition features 121 new chapters and 70 revised ones, focusing on the latest advancements in chiral research across synthesis, catalysis, analytical chemistry, and bioactive compound synthesis. Edited by a world-class editorial board, with contributions from leading experts, Comprehensive Chirality, Second Edition bridges theoretical principles with practical applications, making it an invaluable resource for advanced students, researchers, and professionals.
Key highlights include:
- Innovative Reactions and Methods: advanced diastereo- and enantioselective techniques for controlling stereogenic centers in complex natural products and pharmaceuticals.
- Chiral Auxiliaries and Modern Reagents: transformative uses of chiral auxiliaries and cutting-edge reagents such as hypervalent iodide.
- Catalytic Methodologies: comprehensive coverage of C-C bond formation, emphasizing transition metals, biocatalysis, and multicatalysis.
- Asymmetric Photochemistry: light-induced asymmetric transformations.
- Olefin Functionalization and Cycloaddition: asymmetric oxidation and reduction methods.
- Biocatalysis and Enzyme Engineering: in-depth analysis of enzyme design and engineering as powerful synthesis catalysts.
- Industrial Applications: practical insights into asymmetric synthesis for industrial applications, illustrated through recent case studies.
- Spectroscopic Techniques: updated spectroscopic methods for separating and analyzing enantiomers.
Auflage
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Technology
Zielgruppe
Maße
Höhe: 278 mm
Breite: 215 mm
Gewicht
ISBN-13
978-0-323-90644-9 (9780323906449)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Janine Cossy Molecular, Macromolecular Chemistry and Materials (C3M)
ESPCI Paris, PSL University, CNRS, 75005 Paris, France
Professor Janine Cossy graduated from the University of Reims (France) working under the supervision of Prof. Jean-Pierre Pete. After a postdoctoral stay with Prof. Barry Trost (1980-1982) at the University of Wisconsin (USA), she returned to Reims where she became Director of Research CNRS in 1990. The same year, she moved to Paris to become Professor of Organic Chemistry at the Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris). She has published more than 560 articles and filed 18 patents in the field of synthetic organic chemistry and natural product synthesis. She was Associate Editor at Organic Letters from 2005 to 2018 and since October 2023, she is Tetrahedron Associate Editor. Her research efforts have resulted in more than 560 publications and 18 patents. Among the awards, she received: the CNRS Silver Medal (France, 1996); the UK Royal Society Rosalyn Franklin International Lecturership awarded to internationally recognized women scientists (UK, 2005); the E. C. Taylor Senior Award (2015); the IUPAC 2019 Distinguished Women in Chemistry or Chemical Engineering (2019). She was elected at the French Academy of sciences in 2017 and in 2022, she has been elected at the national Academy of Pharmacy. In addition, she was nominated Chevalier de l'Ordre National du Merite and promoted to Officier in 2018. In 2013, she was nominated Chevalier de la Legion d'Honneur and was promoted to Officier in 2023. She is the co-funder of two companies: CDP-Innovation and Acanthe Biotech.
Affiliations
Molecular, Macromolecular Chemistry and Materials (C3M)
ESPCI Paris, PSL University, CNRS, 75005 Paris, France
Expertise
Development of synthetic methods: Enantioselective reactions, rearrangements, radicals, photochemistry, organometallic reactions, biocatalysis, plasma reactions. Synthesis of natural products and/or bioactive compounds.
Chefredakteur*in / Cheflektor*in
Laboratoire de Chimie Organique, ESPCI, Paris, France
Volume 1 Chiral Pool and Diastereoselective Synthesis
Volume 2 Chiral Auxiliaries
Volume 3 Catalytic Methods for C-C Bond Constructions (to include organocatalysis along with organometallic catalysis)
Volume 4 Asymmetric Photoredox Catalysis
Volume 5 Asymmetric Olefin Functionalization
Volume 6 Asymmetric Cycloadditions
Volume 7 Asymmetric Oxidations-reduction
Volume 8 Enzyme and Biocatalysis
Volume 9 Applications in complex molecule synthesis, pharmaceuticals, and agrochemiclas
