A Selection of the Contents. Features. Evaluation of spectral library searching systems (J.R. Hallowell, Jr., M.F. Delaney). New indexing methods improve the computer retrieval of information on chemical separations (W.J. McDowell). Interface. Laboratory interfacing with a Commodore 64 (D.P. DiLella, R.R. Smardzewski). Expert systems and analytical chemistry (J.W.A. Klaessens et al.). Computer Corner. PROLOG, an artificial intelligence language (D.L. Massart, J. Smeyers-Verbeke). PROLOG, conjunctive queries and rules (D.L. Massart, M. DeSmet). FORTH: a programming environment for on-line instrumentation. UV-Vis spectrophotometer (F.T.M. Dohmen, P.C. Thijssen). AI used for the interpretation of combined spectral data (H.J. Luinge, H.A. van 't Klooster). Biotechnology Focus. Lipid membrane technology for chemical and biosensor development (U.J. Krull, M. Thompson). Trends. Current trends in pesticide residue analysis (T.R. Roberts). Environmental analysis using GC-AAS (R.M. Harrison et al.). Ion-induced spectroscopic methods for analysis of surfaces, interfaces and thin films (H.W. Werner, R.P.H. Garten). Chemical analysis of extraterrestrial material (Yu.A. Surkov, Yu.I. Belyayev). Comparison of approaches to robotics in the laboratory (G.D. Owens, R.A. DePalma). Robotics: a helping hand? (K.J. Leiper). LC with on-line ECD: a viable way to go? (U.A.Th. Brinkman, F.A. Maris). Computer aided optimization in HPLC (L. de Galan). Biomedical applications of energy dispersive X-ray fluorescence (R. Cesareo). State estimation as a chemometrical system (P.C. Thijssen et al.). Some future trends in gas and LC (R.P.W. Scott). Analytical applications of direct chromatographic enantioseparation (S.G. Allenmark). Photoelectrochemical detection in analytical chemistry (W.R. LaCourse, I.S. Krull). Flow injection techniques for flame atomic absorption spectrophotometry (J. Tyson). Applications of polarographic and voltammetric analysis in the fields of agriculture and alimentation (P. Nangniot). Aryl oxalate chemiluminescence detection for HPLC (K. Imai, R. Weinberger). Pharmaceutical analysis using FAB MS-MS (S.E. Unger, T.J. McCormick). Fluorescence optical sensors in analytical chemistry (O.S. Wolfbeis). Next stage in laboratory robotics (T. Hirschfeld). Correlation GC in polymer thermal degradation studies (M. Kaljurand, E. Kullik). Progress in planar chromatography (C.F. Poole). Chemical sensing in the environment (T.E. Edmonds). Comparison of methods for numerical differentiation (S.S. Shukla, J.F. Rusling). Dynamically modified silica - the use of bare silica in reversed-phase HPLC (S.H. Hansen et al.).