The revised fifth edition of Clinical Laboratory Animal Medicine: An Introduction is an accessible guide to basic information for conducting animal research safely and responsibly. It includes a review of the unique anatomic and physiologic characteristics of laboratory animals, husbandry practices, and veterinary care of many animals frequently used in research, including rodents, rabbits, ferrets, zebrafish, nonhuman primates, and agricultural animals.
The updated fifth edition adds two new chapters on zebrafish and large animals, new information on transgenic models and genetic editing, and expanded coverage of environmental enrichment and pain management. The book presents helpful tip boxes, images, and review questions to aid in comprehension and learning, and a companion website provides editable review questions and answers, instructional PowerPoints, additional images not found in the book, and video clips. This important text:
* Provides a complete introduction to laboratory animal husbandry, diseases, and treatments
* Offers a user-friendly format with helpful content that highlights important concepts
* Contains new knowledge relating to technical methodologies, diseases, drug dosages, laws and regulations, and organizations
* Covers information on regulations, facilities, equipment, housing, and research variables as well as veterinary care
* Includes new chapters on zebrafish and cattle, sheep, goats, and pigs
Written for veterinary technicians, veterinary students, practicing veterinarians, and research scientists, the fifth edition of Clinical Laboratory Animal Medicine continues to offer an essential guide to the ethical treatment and anatomic and physiological characteristics of research animals.
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Maße
Höhe: 252 mm
Breite: 178 mm
Dicke: 28 mm
Gewicht
ISBN-13
978-1-119-48956-6 (9781119489566)
Schweitzer Klassifikation
Lesley A. Colby, DVM, MS, DACLAM, is an Associate Professor and Senior Director of Animal Resources and Operations in the Department of Comparative Medicine at the University of Washington in Seattle, Washington, USA.
Megan H. Nowland, DVM, DACLAM, is an Associate Professor in the Unit for Laboratory Animal Medicine at the University of Michigan in Ann Arbor, Michigan, USA.
Lucy H. Kennedy, DVM, DACLAM, is an Assistant Professor in the Unit for Laboratory Animal Medicine at the University of Michigan in Ann Arbor, Michigan, USA.
Autor*in
University of Washington, Seattle, Washington, USA
University of Michigan, East Lansing, Michigan
University of Michigan, East Lansing, Michigan
About the Authors
Preface
About the Companion Web Site
1 Introduction to Laboratory Animal Medicine
Animals Used in Research, Teaching and Testing
Ethical Considerations
Organizations
References
Further Reading
Chapter 1 Review
2 Regulations, Policies, and Principles Governing the Care and Use of Laboratory Animals
Animal Welfare Act and Regulations
Public Health Service Policy on Humane Care and Use of Laboratory Animals
Other Regulations, Policies, Guidance Documents, and Organizations
References
Further Reading
Chapter 2 Review
3 Facility Design, Housing, Equipment, and Management
Laboratory Animal Facility Design
Common Facility Classifications
Housing
Facility Equipment
Management
References
Further Reading
Chapter 3 Review
4 Mice
Genetics
Microbiologic Classifications
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Special Techniques: Transgenic Production Technology
Therapeutic Agents
Introduction to Diseases of Mice
References
Further Reading
Chapter 4 Review
5 Rats
Genetics
Microbiologic Classifications
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Rats
References
Further Reading
Chapter 5 Review
6 Gerbils
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Gerbils
References
Further Reading
Chapter 6 Review
7 Hamsters
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Hamsters
References
Further Reading
Chapter 7 Review
8 Guinea Pigs
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Guinea Pigs
References
Further Reading
Chapter 8 Review
9 Chinchillas
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Chinchillas
References
Further Reading
Chapter 9 Revie
10 Zebrafish
Uses
Behavior
Anatomic and Physiologic Features
Reproduction and Life Stages
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Zebrafish
References
Further Reading
Chapter 10 Review
11 Rabbits
Breeds
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Rabbits
References
Further Reading
Chapter 11 Review
12 Ferrets
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Ferrets
References
Further Reading
Chapter 12 Review
13 Primates
Taxonomy
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Nonhuman Primates
References
Further Reading
Chapter 13 Review
14 Cattle, Sheep, Goats, and Pigs
Uses
Behavior
Anatomic and Physiologic Features
Breeding and Reproduction
Husbandry
Techniques
Therapeutic Agents
Introduction to Diseases of Agricultural Animals of Particular Importance to Research
References
Further Reading
Chapter 14 Review
15 Research Variables, Biosecurity, and Colony Health Surveillance
Research Variables
Biosecurity and Exclusion of Contaminants
Animal Colony Health Surveillance
References
Further Reading
Chapter 15 Review
Appendix 1: Normal Values
Appendix 2: Comparative Biologic and Reproductive Values by Species
Answers to Review Questions
Index