Preface Acknowledgments Introduction t I: Fundamentals of Metabolism Cellular Organelles and Their Metabolic Functions Biological Buffers and Acid-Base Equilibrium Protein Structure Collagen: The Major Connective Tissue Protein Plasma Proteins Membrane Structure and Transport Proteins Hemoglobin Structure and Function General Properties of Enzymes Enzyme Kinetics Regulation of Enzyme Activity Transduction of Hormone Signals Across Membranes Nutritional Basis of Metabolism: Macronutrients Nutritional Basis of Metabolism: Micronutrients t II: Bioenergetics Thermodynamic Principles of Metabolism Oxidative Metabolism Mitochondrial Compartments Catabolic Functions of the TCA Cycle Anabolic Functions of the TCA Cycle Electron Transport Chain: Oxidation of NADH and FADH Oxidative Phosphorylation: Mitochondrial ATP Synthesis Interconversion of Metabolic Fuels t III: Carbohydrate Metabolism Digestion and Absorption of Carbohydrate Effects of Insulin on Blood Glucose Effects of Glucagon on Blood Glucose Glycolysis Metabolic Fate of Pyruvate Glycogen Metabolism Coordinate Regulation of Glycogen Metabolism Gluconeogenesis Coordinate Regulation of Glycolysis and Gluconeogenesis Pentose Phosphate Pathway Galactose, Fructose, and Glucuronic Acid Metabolism Glycosylation of Proteins t IV: Lipid Metabolism Lipid Digestion and Absorption Structure and Function of Lipoprotiens Chylomicron Metabolism VLDL, IDL, and LDL Metabolism HDL Metabolism Cholesterol and Bile Acid Metabolism Steroid Hormone Metabolism Fatty Acid Mobilization and Oxidation Ketone Metabolism Coordinate Regulation of Fatty Acid Metabolism Phospholipids Sphingolipid and Glycolipid Metabolism Essential Fatty Acids and Eicosanoid Metabolism t V: Amino Acid and Nitrogen Metabolism
