Foreword - Remarks from Phil Campbell - Preface; J.Clayton & C.Dennis - PART I: HISTORY - On the Shoulders of Giants : The Quest to Solve DNA? - 1953 Revisited - What Happened Next: The Golden Years of Molecular Biology - PART II: THE PRESENT - Where AreThey Now? - Structural Biology: Still Going Strong - Genomes Galore - Window on Evolution 'Artificial Evolution': Maize, Wheat, Rice Domestication - PART III: THE FUTURE - DNA as a Tool in Disease Diagnosis and Therapy - DNA and Culture - The Genie's Out - PART IV: THE DOUBLE HELIX - 50 YEARS - The Eternal Molecule; C.Dennis &P.Campbell - PART V: FACSIMILE PAPERS FROM NATURE, 25 APRIL 1953 - A Structure for Deoxyribose Nucleic Acid (Nature 171, 737-738; 1953); J.D.Watson & F.H.C.Crick - Molecular Structure of Deoxypentose Nucleic Acids (Nature 171, 738-740; 1953); M.H.F.Wilkins, A.R.Stokes & H.R.Wilson - Molecular Configuration in Sodium Thymonucleate (Nature 171, 740-741; 1953), R.E.Franklin & R.G.Gosling - HISTORICAL BACKGROUND - Quiet Debut for the Double Helix; R.Olby - Discovering Genes are Made of DNA; M.McCarty - DNA and the 'Wronged Heroine'; B.Maddox - PART VI: DNA IN MEDICINE AND SOCIETY - The Mosaic That is Our Genome; S.P??bo - Nature, Nurture and Human Disease; A.Chakravarti & P.Little - The Double Helix in Clinical Practice; J.I.Bell - The Mona Lisa of Modern Science; M.Kemp - PART VII: DNA: THE BIOLOGICAL MOLECULE - Portrait of a Molecule; P.Ball - Ten Years of Tension: Single-Molecule DNA Mechanics; C.Bustamante, - Z.Bryant & S.B.Smith - DNA in a Material World; N.C.Seeman - DNA Replication and Recombination; B.Alberts - DNA Damage and Repair; E.C.Freidberg - The Double Helix and Immunology; G.J.V.Nossal - The Digital Code of DNA; L.Hood & D.Galas - Controlling the Double Helix; G.Felsenfeld & M.Groudine