Part 1 Fluid and electrolytes: introduction to pathophysiology; fluid balance; electrolyte balance; acid-base balance; practical applications - loss of fluid and electrolytes. Part 2 Respiratory system: respiratory system - structure related to disease processes; obstructive pulmonary disorders; restrictive and other pulmonary disorders; practical applications - arterial blood gases. Part 3 Genitourinary system: disorders of the reproductive systems; excretory function - evaluation and control; urinary tract - infection, obstruction and nephrotoxins; glomerular diseases; primary and secondary renal disease; decline in renal function; practical applications - evaluation of renal failure. Part 4 Blood disorders - cells and bleeding: oxygenation and red blood cell disorders. Part 5 Cardiovascular system: blood pressure disorders; vascular disorders; disorders of the heart; congenital heart defects; practical applications - cardiovascular disorders. Part 6 Immune system: nonspecific defense mechanisms; immune system function; detrimental immune responses; immune disorders; practical applications - disorders of immune system. Part 7 Endocrine system: pituitary, thyroid, parathyroid disorders; adrenal and pancreatic endocrine disorders; practical applications - endocrine disorders. Part 8 Gastrointestinal system: disorders of the upper gastrointestinal tract; disorders of the lower gastrointestinal tract; disorders of the liver, gallbladder and pancreas; practical applications - disorders of the liver and pancreas. Part 9 Nervous system: cerebral fluid and vascular disorders; cerebral function disorders; sensory and motor disorders; practical applications - central nervous system disorders.