The book describes the current biophysical understanding of membrane fusion and fission. This includes the basic physics of membrane structure and elasticity, the specific pathways of the intermediate structures of membrane rearrangements and their energies, and the mechanisms by which the specialized proteins induce forces driving fusion and fission reactions. The book is written for graduate students and researchers in the fields of biophysics, biochemistry, biology, and biotechnology and provides the reader with a tutorial like presentation of the physics of lipid membranes necessary for understanding the membrane rearrangements and the analysis of existing phenomenological data on membrane fusion and fission in different systems. The topics are presented from a common viewpoint of required forces, energies and the related tasks for protein machineries.
Sprache
Verlagsort
Zielgruppe
Illustrationen
Maße
Höhe: 240 mm
Breite: 170 mm
ISBN-13
978-3-527-40472-8 (9783527404728)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Michael M. Kozlov, born in 1957, Habil. 1996 Free University, Berlin, Germany; Ph.D. 1984 from Lomonosov University, Moscow; M.S. 1980 from Moscow Engineering Physics Institute. Since 1998, Associate Professor, Sackler Faculty of Medicine, Tel Aviv University. 1996 1998, Senior Lecturer, Sackler Faculty of Medicine, Tel Aviv University 1991 1996, Research Associate, Free University, Berlin, Lab. of W. Helfrich. His research interests are the fields of theoretical biophysics of membranes, elasticity, membrane fusion/fission, lipids, detergents, vesicles, micelles, endocytosis, exocytosis, intracellular trafficking.
Introduction Lipid Membranes Fusion of lipid bilayers Fission of lipid bilayers Fusion of biological membranes Fission of biological membranes Models for membrane fusion Models for membrane fission General Conclusions and Perspectives