Mass Spectrometry in Genetic and Proteomic Analysis

This book details the latest advances in MS-based technologies for large-scale DNA, RNA, protein, and peptide analysis. It illustrates technical concepts step-by-step and introduces specifically designed protocols for different biological systems. Applications discussed include genetic typing, DNA sequencing, sequence validation, large-scale protein identification, high throughput protein quantification, the detection of post-translational modifications, and more. Additional chapters discuss nanotechnology, clinical proteomics, plasma and serum proteomics, and other cutting-edge research areas, making this an excellent reference for researchers who use mass spectrometry for genomic and proteomic analysis.