Section I.- Introductory Remarks: Ruminations on Ovarian Function.- Section II.- Follicular Growth in the Rat: A Reevaluation of the Roles of FSH and LH.- LH-Induced Desensitization of the Adenylyl Cyclase System in Ovarian Follicles.- Gonadal LH receptors: Resolution from Adenylate Cyclase and Transfer to Heterologous Cells.- Prolactin Control of Receptor for Estradiol in Corpora Lutea of Pregnant Rats.- Chairperson's Remarks.- Lateral Mobility and Internalization of Hormone Receptors to Human Chorionic Gonadotropin in Cultured Rat Granulosa Cells.- FSH Stimulation of Mucopolysaccharide Synthesis in Rat and Porcine Ovary.- Immunologic Impairment of ?5-3B Hydroxysteroid Dehydrogenase and Its Effect on Ovarian Function: The Use of a Purified Enzyme.- Receptors for Gonadotrophins in the Ovine Follicle During Growth and Atresia.- Effect of Oestradiol-17? and Gonadotrophins on Prostaglandin Production by Pre-Ovulatory Pig Follicles Superfused in vitro.- LH-Stimulated cAMP Formation in Rat Granulosa Cells During Follicular Maturation - a Non-Refractory Response.- Effect of the Administration of an Ovulatory Dose of HCG on the Subcellular Distribution of Follicular Protein Kinase.- Structural Analysis of Granulosa Cells from Human Ovaries in Correlation with Function.- Regulation of LH(hCG)-Receptor and Adenylate Cyclase in Luteinizing Granulosa Cells.- Changes in Responsiveness of Porcine Granulosa Cells to Prostaglandins and Luteinizing Hormone in Terms of Cyclic-AMP Accumulation During Follicular Maturation.- Some Morphological and Functional Characteristics of Cells of the Porcine Theca Interna in Tissue Culture.- The Control of Ovulation in the Cow by Prostaglandin Inhibitor.- Section III.- Steroidal Modulation of Steroid Secretion in vitro: An Experimental Approach to Intra-Follicular Regulatory Mechanisms.- On the Mechanism of Prolactin Stimulation of Steroidogenesis.- Steroid Secretion by Perifused Ovarian Follicles of Immature, PMSG-Treated Immature, and Mature Rabbits.- Effects of Follicular Development on the Ability of Cultured Porcine Granulosa Cells to Convert Androgens to Estrogens.- Testosterone Synthesis by Chicken Follicular Cells.- Modulation of Thecal Progesterone Secretion by Estradiol-17?.- Chairperson's Remarks.- Steroid Secretion by Ovarian Follicles of Rabbits in Different Reproductive States.- Hormone Requirements for Long-Term Maintenance of Rat Granulosa Cell Cultures.- Long-Term Perfusion of Rabbit Ovarian Follicles.- Estrogen Inhibits Porcine Thecal Androgen Production in vitro.- Antral Follicular and Interstitial Contributions to Progesterone Secretion in the Proestrous Hamster.- Section IV.- Meiotic Maturation of Mouse Oocytes in vitro.- Mammalian Oocyte Maturation: Model Systems and Their Physiological Relevance.- Action of Porcine Follicular Fluid Oocyte Maturation Inhibitor in vitro: Possible Role of the Cumulus Cells.- Relationship Between Steroidogenesis and Oocyte Maturation in Rat Graafian Follicles Cultured in vitro.- Chairperson's Remarks.- The Somatic-Germ Cell Complex.- Rapid Oocyte Death Prior to and at Puberty in Neonatally Thymectomized Mice.- Maturation and Atresia of Human Oocytes in vivo.- Section V.- Follicular Non-Steroidal Regulators.- The Influence of Follicular Fluid on Progesterone Secretion by Porcine Granulosa Cells in vitro.- Inhibition of in vivo and in vitro FSH Secretion by Steroid-Free Hamster Ovarian Extracts.- The Differential Ability of Porcine Follicular Fluid to Suppress Serum FSH in Female Rats from 6 Days of Age to Adulthood.- Evidence for the Presence of a Low Molecular Weight Follitropin Binding Inhibitor in Bovine Follicular Fluid.- Chairperson's Remarks.- Inhibition by Follicular Fluid of Luteinizing Hormone-Sensitive Adenylate Cyclase in Ovarian Plasma Membranes.- Inhibitory Effect of Charcoal-Treated Porcine Follicular Fluid upon Serum FSH Levels and Follicular Development in the Rhesus Monkey.- Follicular Fluid Inhibition of Ovulation.- Modulation of Pituitary Responsiveness to LHRH by Porcine Follicular Fluid: Time and Dose-Dependent Effects.- Isolation and Preliminary Characterization of Inhibin-f.- Evidence that the Pituitary Gland is the Site of Inhibitory Action of Porcine Follicular Fluid upon FSH Secretion in the Rat.- Section VI.- Estrogen Action in the Corpus Luteum.- Follicular Determinants of Corpus Luteum Function in the Human Ovary.- LH Receptors in the Ovine Corpus Luteum During the Estrous Cycle and Early Pregnancy.- Gonadotropin Action in Isolated Ovarian Luteal Cells: The Intermediate Role of Adenosine 3?, 5? Cyclic Monophosphate in Hormonal Stimulation of Progesterone Synthesis.- Chairperson's Remarks.- Changes in Ovarian Mitochondria: Early Indicators of Follicular Luteinization.- Prostaglandin F2? and Progesterone Synthesis in vitro by Bovine Corpora Lutea of Early Pregnancy.- Luteal Phase Deficiencies in Peripubertal Rhesus Monkeys: Mechanistic Considerations.- Cellular Mechanisms Involved in Luteolysis.- Role of Pituitary LH and Placenta in Luteal Progesterone Production and Maintenance of Pregnancy in the Rat.- Relationships Between Cholesterol Supply and Luteal Mitochondrial Steroid Synthesis.- A Comparison of the LH Control of Progesterone Synthesis in Small and Large Cells from Pregnant Cow Corpus Luteum.- Cytochalasin B Inhibition of Luteinizing Hormone Action on Bovine Luteal Cells.- Section VII.- Mechanisms of PGF2? Action in Functional Luteolysis.- Prostaglandin F2? and Its 13-Dehydro Analogs: Comparative Luteolytic Effects in vivo.- Effects of Cholera Toxin, LH, and PGF2? on Steroidogenesis in Luteal Cells.- Effects of Prostaglandin F2?, Estradiol and Luteinizing Hormone in Dispersed Cell Preparations of Bovine Corpora Lutea.- Chairperson's Remarks.- In vitro Release of Progesterone and Prostaglandins F and E by Porcine Luteal and Endometrial Tissue During Induced Luteolysis.- Demonstration of Luteal Cell Membrane Receptors for Prostaglandin F2? by Ultrastructural and Binding Analysis.- Prostaglandin F2? and Progesterone Release in vitro by Ovine Luteal Tissue During Induced Luteolysis.- Section VIII.- Luteal Desensitization: Hormonal Regulation of LH Receptors, Adenylate Cyclase, and Steroidogenic Responses in the Luteal Cell.- Interactions Among Estrogen, Prolactin, and Luteinizing Hormone at the Level of Adenylyl Cyclase in the Corpus Luteum: Findings and Physiological Correlates.- Desensitization and Recovery of PGE2-responsive Ovarian Adenylate Cyclase Modulated by Agents Affecting Cytoskeletal Function.- Inhibitory Effects of Treatment with LHRH or Its Agonists on Ovarian Receptor Levels and Function.- Chairperson's Remarks.- Concluding Remarks.- Lutropin Induced Desensitization of Rat Ovarian Adenylate Cyclase: A GTP-Dependent Process.- hCG-Induced Loss of LH-hCG Receptor and Desensitization of Adenylate Cyclase.- Evidence of a Greater Activity of LH/HCG Binding Inhibitor Present in Aqueous Extracts from Old Compared to Young Porcine Corpus Luteum.- Suppression of Ovarian Function by LHRH and Its Analogues in Pregnant Rats.- Section IX.- Clinical Applications in the Area of Contraceptive Development.- Serum Immunoreactive Relaxin Concentrations in Human Pregnancy, Labor, and the Puerperium.- Effect of Removal of Carbohydrate Residues upon the Half Life and in vivo Biological Activity of Human Chorionic Gonadotropin.- A Procedure for Evaluating Luteolytic Agents in Primates.- Summing Up.- Participants.
