An examination of continuous-flow, atom-bombardment mass spectrometry. Topics covered include design and operation, trace and quantitative analysis, direct analysis of biological processes, analysis of low polarity substances, capillary zone electrophoresis and liquid chromatography.
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
138 line drawings, 5 tables
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Gewicht
ISBN-13
978-0-471-92863-8 (9780471928638)
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Schweitzer Klassifikation
Part 1 Design and operation: design and operational parameters; stable operation; operational advantages; operational disadvantages. Part 2 Trace analysis: instrumentation and methods; optimization of experimetnal parameters; GF-FAB/tandem mass spectrometry of leucine-enkephalin; determination of platelet activating factor (PAF) in cell extract. Part 3 Quantitative analysis: instrumentation; parameters affecting quantitation; focused cesium gun. Part 4 Direct analysis of biological processes: flow injection analysis; batch sample processing; on-line reaction monitoring; microdialysis. Part 5 Liquid chromatography/mass spectrometry: microbore/MS applications; capillary (Nanoscale) LC/MS. Part 6 Capillary zone electrophoresis/mass spectrometry: capillary zone electrophoresis; capillary zone electrophoresis/mass spectrometry. Part 7 Analysis of low polarity substances: probe design; analysis of acetogenins; analysis of metabolites of benzon (A) pyrene; other non-aqueous applications. Part 8 Other applicatons: development of CF-FAB mass spectrometry for the biopharamaceutical industry; biomedical applications of gradient capillary LC/MS using FAB-MS; microbial biotransformations and microcolumn LC/CF-FAB MS for sulfonyurea herbicide metabolite identification; analysis of metabolites of fatty acid oxidation; applications of coaxial CF-FAC MS with tandem mass spectrometry.