Written by leading experts on growth factors and bone cell biology, this volume is an in-depth review of the biological actions and clinical significance of the various growth factors secreted by bone cells. The contributors describe the biological role and regulation of each growth factor, examine its function in skeletal development and maintenance, and discuss its relevance to specific clinical disorders. Full consideration is given to the role of growth factors in the pathogenesis and therapy of metabolic bone disorders. Concluding chapters explore the use of growth factors in treatment of various bone diseases, including osteoporosis
Written by leading experts on growth factors and bone cell biology, this volume is an in-depth review of the biological actions and clinical significance of the various growth factors secreted by bone cells. The contributors describe the biological role and regulation of each growth factor, examine its function in skeletal development and maintenance, and discuss its relevance to specific clinical disorders. Full consideration is given to the role of growth factors in the pathogenesis and therapy of metabolic bone disorders. Concluding chapters explore the use of growth factors in treatment of various bone diseases, including osteoporosis
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Höhe: 254 mm
Breite: 178 mm
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ISBN-13
978-0-7817-2474-6 (9780781724746)
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Schweitzer Klassifikation
Bone Cells and their Function Bone Matrix Biology of Growth Factors Mechanisms of Action of Skeletal Growth Factors in Osteoblasts In Vitro and In Vivo Models to Study Growth Factor Actions in Bone Insulin-like Growth Factors: Their Binding Proteins and Growth Regulation Insulin-like Growth Factors and the Skeleton Clinical Aspects of Insulin-like Growth Factors Biology of Platelet-Derived Growth Factor Platelet-Derived Growth Factor: Skeletal Actions and Regulation Fibroblast Growth Factors and their Receptors Fibroblast Growth Factors and Osteogenesis Fibroblast Growth Factors, Chondrogenesis, and Related Clinical Disorders Hepatocyte Growth Factor Transforming Growth Factor-B Transforming Growth Factor-B in Skeletal Development and Maintenance Activin and Follistatin Activin, Follistatin, and Bone Bone Morphogenetic Proteins Bone Morphogenetic Proteins and Skeletal and Nonskeletal Development Bone Morphogenetic Proteins and the Adult Skeleton The Role of Growth Factors in Fracture Healing Clinical Disorders Associated with Bone Morphogenetic Proteins Parathyroid Hormone-related Protein Role of Parathyroid Hormone-related Protein and Indian Hedgehog in Skeletal Development Osteoprotegerin Nonskeletal Effects of Cytokines Secreted by Bone Cells Colony-Stimulating Factors and Bone Role of Cytokines in Postmenopausal Osteoporosis Role of Cytokines in Osteopetrosis Cytokines, Growth Factors, and Malignancy Clinical Use of Growth Factors Use of Growth Factors for Osteoporotic Therapy Inde
