Part 1 Normal ageing of the nervous system: definition of natural ageing, Barry Snow and Michael Cordes; molecular and neuroendocrine mechanisms in age-related astrocyte activities and neurodegeneration, C. Finch, et al; the natural history of ageing, P. Riederer and K.W. Lange; normal ageing of the nervous system, K.W. Lange and G.M. Paul. Part 2 Parkinson's disease: normality, disturbances and diseases, Donald B. Calne; the pre-clinical phase of Parkinson's disease, Werner Poewe; mitochondria in Parkinson's disease, yoshikuni Mizuno, et al; the biology of toxic events in Parkinson's disease, M.B.H. Youdim; markers for the presence and progression of Parkinson's disease, Peter A. Lewitt; discussion paper on Parkinson's disease, Fabrizio Stocchi. Part 3 Alzheimer's disease: definition of Alzheimer's disease, Elaine Perry and Robert Perry; morphology of the ageing brain and relations to Alzheimer's disease, Kurt A. Jellinger; natural history of Alzheimer's disease, Heiko Braak and Eva Braak; Alzheimer's disease discussion, K. Jendroska. Part 4 Amyotrophic lateral sclerosis: amyotrophic lateral sclerosis - clinical definition and relation to other neurodegenerative disorders, C.W. Olanow; pathogenic mechanisms in amyotrophic lateral sclerosis and otehr motor neuron disorders, P.N. Leigh; xenobiotic biochemistry of neurodegenerative disease with particular attention to methylation pathways, Adrian Williams; the natural history of amyotrophic lateral sclerosis - methodological considerations, Marinos C. Dalakas; amyotrophic lateral sclerosis - discussion, G. Ransmayr.
