This atlas is divided into three main sections. The first section covers the techniques and methods used in preparation of a biopsy. It also covers the normal appearance of muscle biopsy specimens, by both light microscopial and ultrastructural examinations. The second section covers the pathological reactions of the muscle fibres as a totally separate entity, and the third section covers all the major neuromuscular diseases and disorders including X-ray linked recessive myopathies, spinal muscular atrophy, inflammatory myopathies, congenital myopathies and metabolic myopathies.
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
167 schw.-w. u. 176 farb. Abb.
Maße
Höhe: 29.7 cm
Breite: 21 cm
Gewicht
ISBN-13
978-0-7234-2016-3 (9780723420163)
Schweitzer Klassifikation
Part 1 -Introduction. Part 2 - Preparation of the biopsy: Biopsy site; Open muscle biopsy; Needle muscle biopsy; Specimen handling; Preparations for histology, histochemistry and morphometry; Immunocytochemistry; Preparations for electron microscopy; Other methods. Part 3 - Normal muscle structures and analysis of the muscle biopsy: Normal muscle structure; Histochemistry; Anomalies; Ultrastructure; Analysis of the biopsy; Histological assessment; Ultrastructural screening; Quantitative analysis. Part 4 - Pathological reactions of the muscle fibre: Neurogenic disturbances; Primary myopathic disturbances; Metabolic disturbances, Lipid, Glycogen, Mitochondrial; Disturbances of myofibrilla material; Tubular aggregates; Morphological alterations to the nuclei; Miscellaneous ultrastructural disorders. Part 5 - X-linked recessive myopathy (Xp 21.2 myopathy): DMD; BMD; Other X-linked recessive myopathies; Pathological features of Xp 21.2 myopathy. Part 6 - Spinal muscular atrophy: Acute infantile SMA (Type I); Type II SMA; Late life SMA (Type III); Motor neurone disease; Pathology. Part 7 - Inflammatory myopathies: Idiopathic inflammatory myopathy (PM/DM/IBM); Pathological reactions in the inflammatory myopathies. Part 8 - Congenital myopathies: Pathology of the congenital myopathies; Congenital muscular dystrophy; Congenital fibre-type disproportion; Centronuclear myopathy; Nemaline myopathy; Core myopathies; Intra-uterine maturational delay; Type I fibre hypertrophy. Part 9 - Metabolic disorders: Pathological reactions in metabolic myopathies; Glycogen storage diseases; Lipid myopathis; CPT deficiency; Mitochondrial myopathies. Part 10 - Miscellaneous disorders: Motor neurone disease; Parasitic infections; Myotonic dystrophy; Endocrine disorders; Drugs, toxins and trauma. Part 11- Appendix - Recipe for all muscle strains. Part 12 - Index.
