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This volume is unique in bringing the exciting range of antidepressant treatment developments together with a focus on their neurobiological mechanisms and how these interact with the known pathophysiology of depression. Current evidence for treatment efficacy is reviewed together with a discussion of where in the management pathway of this common condition, these new approaches might take their place.
SSRIs A pharmacological cul-de-sac.- Neurobiology of SSRI withdrawal.- Pramipexole in the treatment of depression.- Opioid mechanisms in the treatment of depression.- Neuropsychological effects of antidepressants-translational studies.- KETAMINE FOR MAJOR DEPRESSIVE DISORDER.- Psilocybin and other classic psychedelics in depression.- Gut-brain axis and antidepressant treatment.- Anti-inflammatory drugs in the treatment of depression.- Mechanisms of TMS in Depression.- Mechanism of action of ECT in depression.- Vagal nerve stimulation in the treatment of depression.
