1. Neurobiology of Anxiety and Panic.- 2. Molecular Forms and Regional Distribution of Cholecystokinin in the Central Nervous System.- 3. Animal Studies on CCK and Anxiety.- 4. Cholecystokinin and Panic Disorder.- 5. Psychological Factors and Response to Cholecystokinin.- 6. Interactions Between Cholecystokinin and Other Neurotransmitter Systems.- 7. CCK, Addiction and Anxiety.- 8. Opioid and CCK Systems in Anxiety and Reward.- 9. Summary and Future Directions.