Part 1 General principles: characteristics of drug action; factors affecting responses to drugs; the principles of synaptic transmission. Part 2 The peripheral nervous system: the somatic motor system; drugs affecting neuromuscular transmission; the autonomic nervous system; drugs affecting the parasympathetic and the sympathetic systems; drugs with non-synaptic actions. Part 3 The central nervous system: synaptic transmission in the central nervous system; anaesthetics, hypnotics and sedatives; neuroleptic drugs; anti-anxiety drugs; anticonvulsant drugs; analgesic drugs; central stimulant drugs; drugs used in the treatment of affective disorders; psychotomimetic drugs and drugs of abuse; drugs used in the treatment of neurological disorders; miscellaneous centrally acting drugs.