This prostate biopsy book is aimed at practising pathologists. The text and collection of tables and photomicrographs are provided to continue efforts to recognize, understand and accurately interpret the light-microscopic findings in difficult prostate biopsy specimens. This book is intended as a practical aid to complement textbooks of urological pathology or other sources of information in the area.
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
ISBN-13
978-0-412-75510-1 (9780412755101)
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Schweitzer Klassifikation
Normal anatomy and histology: anatomy and histology of the prostate; seminal vesicles and ejaculatory ducts; Cowper glands; immunohistochemistry; prostate sampling techniques. Inflammation: acute bacterial prostatitis; chronic prostatitis; granulomatous prostatitis; AIDS-related prostatitis; pathological changes following needle biopsy. Non-neoplastic metaplasia: squamous metaplasia; mucinous metaplasia; neuroendocrine cells with eosinophilic granules; urothelial metaplasia (transitional metaplasia); nephrogenic metaplasia (nephrogenic adenoma). Hyperplasia and nodular hyperplasia: usual acinar and stromal hyperplasia; atrophy and postatrophic hyperplasia; stromal hyperplasia with atypical giant cells; basal cell hyperplasia and basal cell proliferations; cribriform hyperplasia; atypical adenomatous hyperplasia; sclerosing adenosis; verumontanum mucosal gland hyperplasia; hyperplasia of mesonephric remnants; association of nodular hyperplasia and prostate cancer. Miscellaneous benign lesions and cysts: amyloidosis; pigmented lesions; endometriosis; prostatic cyst; ejaculatory duct adenofibroma. Prostatic intraepithelial neoplasia (PIN): diagnostic features of PIN; PIN after therapy; clinical significance of PIN; serum PSA and PIN; histochemistry and immunohistochemistry of PIN; neovascularization in PIN; differential diagnosis of PIN. Adenocarcinoma: diagnosis of carcinoma; eight common problems in needle biopsy interpretation; needle biopsy findings; prostate-specific antigen (PSA) and early detection of cancer; clinical and pathological staging of cancer; tumour track seeding. Grading: Gleason grading system; grading needle biopsies; reproducibility of Gleason grading and comparison with other grading systems; proposed modifications to Gleason grading; clinical significance of grading. Variants of prostatic adenocarcinoma: ductal carcinoma; mucinous carcinoma (colloid carcinoma); signet-ring-cell carcinoma; carcinoma with neuroendocrine differentiation; neuroendocrine carcinoma (small cell carcinoma and carcinoid); squamous cell and adenosquamous carcinoma; sarcomatoid carcinoma (carcinosarcoma; metaplastic carcinoma); adenoid cystic carcinoma/basal cell carcinoma; lymphoepithelioma-like carcinoma; carcinoma with oncolytic features; comedocarcinoma;cribriform carcinoma. (Part contents).
