Metabolic Control and Disease

thorough examination of the topic. Part I of the text emphasizes general mechanisms of metabolic control and contains information on gene structure and function, inherited metabolic variation and disease, the molecular basis of hormone action, and the chemical interactions among major metabolic pathways; Part II reviews the many classes of disorders of intermediary metabolism, focusing both on the importance of genetic control systems in disease etiology and on the critical interaction between heredity and environment; and Part III details the organization of the endocrine system, with discussions of its many abnormalities built upon a strong foundation in the basic medical sciences.