Understanding the mechanisms that underlie brain activity and function remains one of the major frontiers of biology. All the processes of how we co-ordinate our movements, sense our surroundings, react to stimuli and learn and retain information rely on complicated networks of neurons that communicate with each other and their targets. This fast and accurate intercellular signalling mostly occurs at synapses, specialized processes of neurons that release chemical signals, called neurotransmitters. This volume provides the reader with extensive background information on neurotransmitter release. It takes a multidisciplinary approach, but does not assume previous knowledge having basic introductions to most topics. Topics however are covered in enough detail to be of interest to experts in the field. Throughout, emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
colour and b&w illustrations, index
ISBN-13
978-0-19-963767-6 (9780199637676)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
1: Kelly: An overview of neurotransmitter release; 2: Fisher and Oberhauser: Techniques for elucidaing the secretory process; from Ca++ entry to exocytosis; 3: Hazuka, Foletti and Scheller: ; 4: Martin: The role of phospholipids in neurosecretion; 5: Krants, Chaudhry and Edwards: Neurotransmitter transporters; 6: O'Kane, Schiavo and Sweeney: Toxins that affect neurotransmitter release; 7: Burns and Augustine: Functional studies of presynaptic proteins at the squid giant synapse; 8: Nonet: Studying mutants that affect neurotransmitter release in C. elegans ; 9: Pennetta, Wu and Bellen: Dissecting the molecular mechanisms of neurotransmitter release in Drosophila ; 10: Lloyd & Bellen: Genetic analysis of neurotransmitter release in mice and humans; 11: Zhang & Ramaswami: Synaptic vesicle endocytosis and recycling.