Part 1 General analytical principles: practising regional science; principles of spatial modeling; modeling service activities. Part 2 Producer services: classifying services - the heterogeneity problem; producer vs consumer services; producer services and office location; the office location problem; modelling the office location decisions; output structures and location; choosing between discrete points, a location triangle; office location and national urban hierarchies. Part 3 Spatiial service flows: trade in producer services; the channels of interregional trade in producer services; estimating interregional producer service flows; regional comparative advantage and services; socio-cultural barriers to producers service flows. Part 6 Consumer services: first approaches; evaluating flows of goods and services; spatial consumption behaviour and its modelling; public services; consumer services growth and concentration. Part 5 A case in spatial econometrics: power transformed variables; using elasticities; further application. Part 6 General conclusions - towards a global approach: interdisciplinary aspects; service activities and production systems; alternative frameworks for analysis.