Cajal has been called the "Father of Neuroscience" and his personal view of the neuron has dominated the field for over 100 years. No single person has been able to challenge his global perspective of the neuron gained by Cajal's work in neuroanatomy, development, physiology, evolution and medicine. However, over 30 neuroscientists from around the world have accepted the challenge of writing a review article on "Changing Views of Cajal's Neuron". Many of these experts admitted they could only add to Cajal's theory and they carefully provided their new findings based on modern methods of microscopy, molecular biology or neurobiology. Other experts recognized specific areas where Cajal's ideas of neurons needed to be altered and refined. Key knowledge necessary to understand plasticity or development is now available and permits a changed view. A few of the authors directly challenged some of the most widely accepted and cherished theories of Cajal: the neuron as an isolated unit, function of dendrites, the direction of electrical conductivity and the importance of plasticity in the adult brain.
In total, the collection of articles provides a perspective on the enormous force of Cajal's genius in the 21st-century view of the neuron.
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Elsevier Science & Technology
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Für Beruf und Forschung
Für höhere Schule und Studium
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ISBN-13
978-0-444-50815-7 (9780444508157)
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Schweitzer Klassifikation
Herausgeber*in
Departments of Biology and Psychiatry, Center for Neural Science, New York University, USA
Instituto Cajal (CSIC), Madrid, Spain
Center for Neuroscience, University of California, Davis, USA
Department of Neurobiology, Yale University School of Medicine, New Haven, USA
Department of Anatomy and Neurobiology, University of California, College of Medicine, Irvine, USA
Neuronal changes during development and evolution; Inside the neuron - cytoskeleton, dendrites and synapses; Character and function of specific neurons; Mechanisms of neuronal birth, growth and death; Complex connections and organization; Functional circuits, mental diseases and brain ageing.