This textbook provides an introduction to modern cellular and molecular immunology for undergraduate science students and for clinicians. Jonathan Austyn and Kathryn Wood have adopted the approach of arranging the book around a "map" of the immune system, with each chapter focusing on a different aspect. This has allowed them to present the information in a logical order, drawing together diverse threads to illustrate the emerging principles of the subject.;The book first follows the fate of antigens through different cellular compartments until they are expressed on the surface of antigen presenting cells and are recognized by T cells, then analyzes the cellular and molecular basis of each of the components of the immune response in turn and discusses immune regulation. It ends with an appendix that illustrates the techniques used in immunological research. In this way, the book builds up a picture of this complex subject, explaining current concepts and indicating topics for debate.
The result is a book that may also be used by postgraduate students in immunology and related disciplines who need and overview of the subject, and by researchers who need an insight into the subject
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
309 line drawings, 11 half-tones, index, bibliography
ISBN-13
978-0-19-854297-1 (9780198542971)
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Schweitzer Klassifikation
The major histocompatibility complex; antigen presenting cells; the molecular basis of T cell responses; the T cell repertoire; antigen receptors - structure and function, genes and the immunoglobulin superfamily; B cells and antibody responses; inflammatory mediators and soluble effector mechanisms; cellular cytotoxicity; idiotype networks.
