This is the first book to deal comprehensively with endocrine toxicology. It covers the whole spectrum of known toxicant effects on the endocrine system ranging from small disturbances in hormonal secretion to full endocrine neoplasia. In each chapter, internationally recognised authorities have addressed basic endocrine physiology, current techniques for studying endocrine toxicity in vivo and in vitro, known xenobiotic-induced toxicity phenomena and the latest scientific advances in understanding the underlying molecular and cellular events. Consideration is given to important issues such as dietary factors which influence endocrine toxicity, species differences in sensitivity to toxicants, and the toxicity of hormones and drugs. The volume provides a sound basis for understanding the scientific aspects of this complex and important area of toxicology and will be a useful source of information for all those working in this field.
Rezensionen / Stimmen
' ... well-balanced and well-written ... The book is to be recommended as an introduction to toxicology for the endocrinologists, but probably is of greater value as an introduction to endocrinology for the toxicologist!' Barry Furr, The Endocrinologist 'This is such an excellent volume that the appreciation printed on the back cover could be repeated by any reviewer without hesitation. It is the first target toxicity volume dedicated to endocrine toxicology and it covers the whole spectrum of known toxic effects on the endocrine system.' L. Magos, Journal of Applied Toxicology
Sprache
Verlagsort
Zielgruppe
Maße
Höhe: 236 mm
Breite: 156 mm
Dicke: 28 mm
Gewicht
ISBN-13
978-0-521-40225-5 (9780521402255)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
1. Introduction to endocrine toxicology C. K. Atterwill and J. D. Flack; Part I. Hypothalamic and Pituitary Toxicology: 2. Anatomy and morphology of the pituitary gland in different species - implications in toxicology R. W. Greenhill; 3. Toxic effects of xenobiotics on the pituitary gland R. Walker and R. Cooper; 4. Hypothalamus and pituitary gland - xenobiotic induced toxicity and models for its investigation J. Buckingham and G. Gillies; Part II. Thyroid and Parathyroid Toxicology: 5. Thyroid gland I - physiolocial control and mechanism of carcinogenseis G. Thomas and E. D. Williams; 6. Thyroid gland II - mechanisms of species-dependent toxicity, hyperplasia and neoplasia induced by xenobiotics C. K. Atterwill, C. Jones and C. G. Brown; 7. Pathophysiology and xenobiotic toxicity of parathyroid gland in animals C. C. Capen; Part III. Adrenal Toxicology: 8. Toxicology of the adrenal gland H. Colby and P. A. Longhurst; Part IV. Reproductive Toxicology: 9. Endocrine toxicology of the male reproductive system D. Garside and P. Harvey; 10. Endocrine toxicology of the female reproductive system C. A. Wilson and A. J. Leigh; Part V. Other Endocrine Toxicological Factors: 11. Dietary effects on endocrine tumours M. J. Tucker; 12. Toxicology of the diffuse neuroendocrine system G. R. Betton; 13. Conclusions and new vistas F. Roe and A. Dayan; Index.
