Integrating the monoamine systems; electrophysiology of brain noradrenaline neurons and mode of action of antidepressant drugs; possible role of 5HT1B autoreceptors; modulation of the serotonergic system by 5HT moduline; antidepressants and post-receptor events; animal models of depression; disorder of synaptic homeostasis as a cause of depression and a target for treatment; norepinephrine and serotonin in antidepressant action; serotonin, impulse control and alcoholism; pharmacological challenge tests and brain serotonin function in depression and during SSRI treatment; prevalence of depression; existing therapies with newer antidepressants; antidepressant drugs and sexual function; non-pharmacological treatments; adjunct treatments; synergistic effects of serotonergic and noradrenergic antidepressants; suicide prevention; resistant depression; which antidepressant?
