Part 1 Clinical and biological studies of poorly responsive patients: characteristics of Kraepilinian Schixophrenia and their relation to pre-morbid socio-sexual functioning, Richard S.E.Keefe et al; Catecholamine Metabolites in plasma as correlates of neuroleptic response, Malcolm B.Bowers Jr, M.D.; positron emission tomography in the study of neuroleptic response, Adam Wolkin M.D. Part 2 Refinements of neuroleptic treatment: schizophrenia - alternative neuroleptic strategies, Celeste A.Johns et al; neuroleptic plasma levels in treatment-resistant schizophrenic patients, Theodore Van Putten, et al. Part 3 Treatment for neuroleptic refractory patients: Benzodiazepine augmentation of neuroleptics, Owen M.Wolkowitz et al; lithium and carbamazepine augmentation in treatment-refractory schizophrenia, S.Charles Schulz et al; pre-synaptic modulators of dopamine synthesis in the treatment of chronic schizophrenia, Jeffrey L.Berland M.D., Ph.D.; Clozapine in refractory schizophrenia, John M.Kane et al.