Part 1 Macrophage and viral infection: regulation of cytokine and viral gene expression in monocytes infected with the human immunodeficiency virus; AIDS encephalopathy and tropism of HIV for brain monocytes/macrophages and microglial cells; secretory repertoire of HIV infected human monocytes/macrophages; interaction of cultured human Kupffer cells with HIV-infected CEM cells - an electron microscopic study; influenza A virus infects macrophages and stimulates release of tumour necrosis factor-alpha; regulation by endogenous interferon of virus-induced cytokine gene expression in mouse acrophages. Part 2 Macrophages as tumour cytotoxic effector cells: the role of macrophages in the regulation of primary tumour growth; monocyte-mediated growth control and the induction of tumour cell death; tumouricidal effector molecules of murine macrophages; antibody-mediated tumour cytotoxicity of microglia; adoptive immunotherapy with autologous macrophages - current status and future perspectives; treatment of cancer patients with endotoxin induces release of endogenous cytokines. Part 3 Macrophage biochemistry and molecular biology: a membrane-round form of the acute-phase protein; C-reactive protein is the galactose-specific particle receptor on rat liver macrophages; biochemistry and function of pteridine synthesis in human and murine macrophages; regulation of nitric oxide production by stimulated rat Kupffer cells; regulation of M-CSF expression by M-CSF - role of protein kinase C and transcription factor NF-B; the c-fgr proto-oncogene - expression in Epstein-Barr-virus-infected B lymphocytes and in cells of the myelomonocytic and granulocytic lineages; increased methylation of c-fms protooncogene in acute myelomonocytic leukemias.
