Macrophage 1990

Part 1 Macrophage heterogeneity and differentiation: influence of interleukin-2 on the differentiation of macrophages; differentiation of human monocytes in CD14 negative accessory cells - do dendritic cells derive from the monocytic lineage?; monocytes and regular monocytes in human blood; cytokine regulation of the myeloid glycoprotein CD14; synthesis of complement components C2 and C4 by human monocyte-derived macrophages during in vitro differentiation in serum-free culture conditions. Part 2 Macrophages in the pathogenesis of disease: new insights into the immunopathology of tuberculosis; the macrophage in tuberculosis - sinner or saint? - the T cell decides; phagocytosis and heat shock response in human monocytes-macrophages; intracellular pathogens and professional phagocytes in reactive arthritis; activation of monocytes during inflammatory bowel disease; low incidence of transplant-related complications in patients with chronic release of tumour necrosis factor-alpha before admission to bone marrow transplantation; a clinical correlate of cytokine desensitization. Part 3 Macrophages and antimicrobial defence: tumour necrosis factor-alpha - central regulatory cytokine in the induction of macrophage antimicrobial activities; regulatory mechanisms of host responsiveness to endotoxin (lipopolysaccharide); microbicidal activities of salmonella typhimurium - and interferon-gamma-activated mouse peritoneal macrophages; formation of interferon-gamma and tumour necrosis factor in mice during salmonella typhimurium infection; lipopolysaccharide-instructed, cryopreserved, human monocytes sequentially convert plasma fibrinogen to fibrin and analyze the fibrin formed.