Preface ; 1. The Role of Antioxidants in Human Health ; Saikat Sen and Raja Chakraborty ; 2. Pathophysiological Implications of Altered Redox Balance in HIV/AIDS Infection: Diagnosis and Counteract Interventions ; L. Gil del Valle, Ph.D. ; 3. Thermodynamics of Free Radical Reactions and the Redox Environment of a Cell ; Klaudia Jomova and Marian Valko ; 4. Oxidative Stress in the Metabolism of Estrogens Leading to Cancer Initiation: Prevention by Specific Antioxidants ; Eleanor G. Rogan and Ercole L. Cavalieri ; 5. Polyphenol Compounds as Antioxidants for Disease Prevention: Reactive Oxygen Species Scavenging, Enzyme Regulation, and Metal Chelation Mechanisms in E. coli and Human Cells ; Hsiao C. Wang and Julia L. Brumaghim ; 6. DNA-Protective Mechanisms of Glutathione Intervention in Catechol-Mediated Oxidative DNA Damage in the Presence of Copper(II) Ions ; Maria Hepel, Magdalena Stobiecka, Janet Peachey, and Jeremiah Miller ; 7. Antioxidant Effectiveness in Preventing Paraquat-Mediated Oxidative Dna Damage in the Presence of H2O2 ; Magdalena Stobiecka, Amanda Prance, Kaitlin Coopersmith, and Maria Hepel ; 8. Artificial Nanoparticle Antioxidants ; Erica Sharpe, Daniel Andreescu, and Silvana Andreescu ; 9. Cerium Oxide Nanoparticles for the Treatment of Neurological Oxidative Stress Diseases ; A. Y. Estevez and J. S. Erlichman ; 10. Detection of Superoxide and Hydrogen Peroxide from Living Cells Using Electrochemical Sensors ; Szilveszter Gaspar ; 11. Peroxynitrite and Nitroxidative Stress: Detection Probes and Micro-Sensors. A Case of a Nanostructured Catalytic Film ; Serban F. Peteu, Saleem Banihani, Mutha M. Gunesekera, Pubudu Peiris, Oana A. Sicuia, and Mekki Bayachou ; 12. Blue Native PAGE and Mass Spectrometry as an Approach for the Investigation of Stable and Transient Protein-Protein Interactions ; Alisa G. Woods, Izabela Sokolowska, Rama Yakubu, Melissa Butkiewicz, Martin LaFleur, Christopher Talbot, and Costel C. Darie ; 13. Mass Spectrometry for Proteomics-Based Investigation of Oxidative Stress and Heat Shock Proteins ; Izabela Sokolowska, Alisa G. Woods, Jessica Wagner, Jeannette Dorler, Kelly Wormwood, Johannes Thome, and Costel C. Darie ; Editors' Biographies ; Author Index ; Subject Index