Immunointervention in Type 1 diabetes - hope for prevention, D.Andreani; rationale of immune intervention in type 1 diabetes, J. Nerup; immunotherapy in organ-specific autoimmune diseases - success or failure, L.Bonomo; a new look to the mechanism of action of steroid hormones on the immune system, A.Gulino et al; mechanisms of action of anti-T-cell monoclonal antibodies, H.Waldmann; immunomodulators - mechanisms of action and guidelines for treatment, P.Pozzilli et al; cyclosporin treatment in diabetes, J.F.Bach; a critical evaluation of immunosuppression trials in Type 1 diabetes, J.Dupre and C.R.Stiller; a critical evaluation of immunomodulation trials in recent-onset Type 1 diabetes, G.Pozza and A.Secchi; metabolic and immunological parameters for monitoring immunotherapy in Type 1 diabetes, G.D.Bompiani et al; intensive insulin therapy and sustained remission in Type 1 diabetes mellitus, P.Brunetti and G.B.Bolli; new lines of intervention in Type 1 diabetes, L.C.Harrison; prediction of Type 1 diabetes - the Bart's-Windsor family study, P.J.Bingley and E.A.M.Gale; prediction of Type 1 diabetes and attempts at prevention - the Joslin study, G.S.Eisenbarth; - the Gainesville study, N.K.Maclaren; prediction of Type 1 diabetes and attempts at prevention - the Dusseldorf/Karlsburg study, H.Kolb; prediction of Type 1 diabetes - the Rome family study, G. Ghirlanda et al; immunodeficiency in long-standing diabetes - evidence and approaches to prevention, N.Visalli et al. Appendix: registry of Published Immune Intervention Trials in Type 1 diabetes with complete addresses of authors.