Part 1 Overview: Benign by design chemistry, Paul T. Anastas; environmentally benign chemical synthesis and processing for the economy and the environment, Kenneth G. Hancock and Margaret A. Cavanaugh. Part 2 Benign chemistry - research: microbial biocatalysis - synthesis of adipic acid from d-glucose, Karen M. Draths and John W. Frost; mechanistic study of a catalytic process for carbonylation of nitroaromatic compounds - developing alternatives for use of phosgene, Wayne L. Gladfelter and Jerry D. Gargulak; preparative reactions using visible light - high yields from pseudoelectrochemical transformation, Gary A. Epling and Qingxi Wang; a photochemical alternative to the Friedel-Crafts reaction, George A. Kraus et al; Mn(III)-mediated electrochemical oxidative free-radical cyclizations, Barry B. Snider and Bridget A. McCarthy; supercritical carbon dioxide as a medium for conducting free-radical reactions, James M. Tanko et al; the University of California-Los Angeles styrene process, Orville L. Chapman. Part 3 Benign chemistry - industrial applications: generation of urethanes and isocyanates from amines and carbon dixoide, Dennis Riley et al; nucleophilic aromatic substitution for hydrogen- new halide-free routes for production of aromatic amines, Michael K. Stern; chemistry and catalysis - keys to environmentally safer processes, Leo E. Manzer. Part 4 Tools for assessment of benign chemistry: alternative syntheses and other source reduction opportunities for premanufacture notification substances at the US Environmental Protection Agency, Carol A. Farris et al; computer-assisted alternative synthetic design for pollution prevention at the US Environmental Protection Agnecy, Paul T. Anastas et al.